GSE85[Accession] - GEO DataSets

Select item 2000000851.

wild type and aire -/- murine meduallary thymic epithelial cells

(Submitter supplied) Mice used were B6/129 F2's, 3-5 weeks of age, either wild type or with both copies of the autoimmune regulator gene (aire, GenBank #AF079536) disrupted. Thymi from five of these mice of both sexes were removed and pooled. After collagenase/dispase digestion, density gradient fractionation, and fluorescent antibody staining, cells with the phenotype CD45-, G8.8+, CDR1int and B7.1hi were FACS-sorted and total RNA was made from them. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS167
Platform:: GPL81
6 Samples

Download data: CEL

Series

Accession:: GSE85

ID:: 200000085

Select item 1672.

Autoimmune disease mechanisms

Examination of medullary thymic epithelial cells from aire-deficient mice. aire is autoimmune regulator gene. Aim to understand autoimmune disease mechanisms, esp. autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED).

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 strain sets

Platform:: GPL81
Series:: GSE85
6 Samples

Download data: CEL

DataSet

Accession:: GDS167

ID:: 167

Select item 1000000813.

[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The MG-U74 set includes 3 arrays with a total of 36899 entries and was indexed 29-Jan-2002. more...