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Items: 4

1.

A mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
Platforms:
GPL13112 GPL8321
12 Samples
Download data: CEL
Series
Accession:
GSE53685
ID:
200053685
2.

A mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia [array]

(Submitter supplied) The plasma cell transcription factor XBP1 is critical for terminal differentiation of B cells into plasma cells but has no known role at earlier stages of B-cell development. Here we show that XBP1 is not only important during early B-cell development and for survival of pre-B cells but also protects pre-B ALL cells. Among pre-B ALL subset, XBP1 was hypomethylated and highest expressed in the Ph+ ALL subset. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL8321
6 Samples
Download data: CEL
Series
Accession:
GSE53684
ID:
200053684
3.

[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A 2.0 Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...
Organism:
Mus musculus
66 DataSets
523 Series
2 Related Platforms
6974 Samples
Download data
Platform
Accession:
GPL8321
ID:
100008321
4.

BCR-ABL1 transformed murine ALL-like cells, Grp78 wild type, replicate 1

Organism:
Mus musculus
Source name:
mouse Grp78fl/fl cells transduced with p190 (BCR-ABL1) and an empty vector (EV), Grp78 wild type
Platform:
GPL8321
Series:
GSE53684 GSE53685
Download data: CEL
Sample
Accession:
GSM1298807
ID:
301298807
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