GSM146310[Accession] - GEO DataSets

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Items: 4

Select item 2000063211.

Analysis of CD38+ and CD38- sub-clones derived from the same CLL patient

(Submitter supplied) CD38 expression is an important prognostic marker in CLL with high levels of CD38 associated with shorter overall survival. In this study, we used gene expression profiling and protein analysis of highly purified cell-sorted CD38+ and CD38- chronic lymphocytic leukemia cells to elucidate a molecular basis for the association between CD38 expression and inferior clinical outcome. Paired CD38+ and CD38- CLL cells derived from the same patient were shown to be monoclonal by VH gene sequencing but despite this, CD38+ CLL cells possessed a distinct gene expression profile when compared with their CD38- sub-clones. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2676
Platform:: GPL571
12 Samples

Download data: CEL

Series

Accession:: GSE6321

ID:: 200006321

Select item 26762.

CD38-positive and CD38-negative chronic lymphocytic leukemia cells

Analysis of paired CD38(+) and CD38(-) chronic lymphocytic leukemia (CLL) cells from six patients. CD38 expression is an important prognostic marker in CLL with high levels of CD38 antigen associated with shorter overall survival. Results provide insight into the molecular basis of this association.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 cell type, 6 individual sets

Platform:: GPL571
Series:: GSE6321
12 Samples

Download data: CEL

DataSet

Accession:: GDS2676

ID:: 2676

Select item 1000005713.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...