GEO DataSets

(Submitter supplied) We developed a general approach to small molecule library screening called GE-HTS (Gene Expression-Based High Throughput Screening) in which a gene expression signature is used as a surrogate for cellular states and applied it to the identification of compounds inducing the differentiation of acute myeloid leukemia cells. In screening 1,739 compounds, we identified 8 that reliably induced the differentiation signature, and furthermore yielded functional evidence of bona fide differentiation. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL96 GPL80

117 Samples

Download data: CEL

(Submitter supplied) We developed a general approach to small molecule library screening called GE-HTS (Gene Expression-Based High Throughput Screening) in which a gene expression signature is used as a surrogate for cellular states and applied it to the identification of compounds inducing the differentiation of acute myeloid leukemia cells. In screening 1,739 compounds, we identified 8 that reliably induced the differentiation signature, and furthermore yielded functional evidence of bona fide differentiation. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL80

21 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Has 7129 entries and was indexed 29-Jan-2002. Probes represent approximately 5,000 full-length human sequences. Keywords = high density oligonucleotide array July 08, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site

Organism:

Homo sapiens

19 DataSets

57 Series

1490 Samples

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