GSM2441459[Accession] - GEO DataSets

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Items: 4

Select item 2000929851.

Reprogramming methods influence DNA methylation and expression patterns of mouse induced pluripotent stem cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platforms:: GPL21103 GPL17021
12 Samples

Download data: BED, FPKM_TRACKING

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Accession:: GSE92985

ID:: 200092985

PubMed Full text in PMC Similar studies

Select item 2000929832.

Reprogramming methods influence DNA methylation and expression patterns of mouse induced pluripotent stem cells [RNA-seq]

(Submitter supplied) Induced pluripotent stem cells (iPSCs) can be derived from somatic cells through ectopic expression of transcriptional factors or chemical cocktails. Chemical reprogramming might be safe than transcriptional factors since there is no integration of exogenous genes. However, there is still little direct evidence to prove this hypothesis. In this study, we have performed whole genome profiling of the DNA methylomes of mouse chemical iPSCs (CiPSCs), transcriptional factors induced iPSCs (TF-iPSCs) and embryonic stem cells (ESCs). more...