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Items: 4

1.

The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
4 related Platforms
246 Samples
Download data: RCC
Series
Accession:
GSE101689
ID:
200101689

Analyze with GEO2R

2.

The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases II

(Submitter supplied) Microglia play a pivotal role in the maintenance of brain homeostasis, but lose their homeostatic function during the course of neurodegenerative disorders. We identified a specific APOE-dependent molecular signature in microglia isolated from mouse models of amyotrophic lateral sclerosis, multiple sclerosis and Alzheimer’s disease (SOD1, EAE and APP-PS1) and in microglia surrounding neuritic A-plaques in human Alzheimer’s disease brain. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL23812
56 Samples
Download data: RCC
Series
Accession:
GSE101687
ID:
200101687

Analyze with GEO2R

3.

NanoString nCounter Mouse Gene Expression Custom Chip MG534

(Submitter supplied) See manufacturer's website (www.nanostring.com)
Organism:
Mus musculus
2 Series
56 Samples
Download data
Platform
Accession:
GPL23812
ID:
100023812

4.

SOD1:Trem2het_03

Organism:
Mus musculus
Source name:
FACS sorted MG cells
Platform:
GPL23812
Series:
GSE101687 GSE101689
Download data: RCC
Sample
Accession:
GSM2712116
ID:
302712116

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