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Items: 3

1.

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis

(Submitter supplied) mRNA quality control mechanisms ensure fidelity of protein translation. An evolutionarily conserved component of the quality control machinery, Dom34/Pelota (Pelo), rescues stalled ribosomes. Here we show that Pelo is required for mammalian epidermal homeostasis. Our study reveals a novel role for the ribosome-rescue machinery in mammalian tissue homeostasis and an unanticipated specificity in its impact on different stem cell populations.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21103
17 Samples
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Series
Accession:
GSE106246
ID:
200106246

PubMed Similar studies SRA Run Selector

2.

Illumina HiSeq 4000 (Mus musculus)

Organism:
Mus musculus
6612 Series
142150 Samples
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Platform
Accession:
GPL21103
ID:
100021103

3.

Pelo -/- Lgr6 replicate 1

Organism:
Mus musculus
Source name:
Epidermis
Platform:
GPL21103
Series:
GSE106246
Download data
Sample
Accession:
GSM2832756
ID:
302832756

SRA Run Selector

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db=gds|term=GSM2832756[Accession]|query=1|qty=2|blobid=MCID_674aa6c380f8cd4e914323a8|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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