GSM290420[Accession] - GEO DataSets

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Items: 4

Select item 2000115241.

The platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease

(Submitter supplied) In sickle cell disease, ischemia-reperfusion injury and intravascular hemolysis produce endothelial dysfunction and vasculopathy characterized by reduced nitric oxide (NO) and arginine bioavailability. Recent functional studies of platelets in patients with sickle cell disease reveal a basally activated state, suggesting that pathological platelet activation may contribute to sickle cell disease vasculopathy. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3318
Platform:: GPL570
30 Samples

Download data: CEL

Series

Accession:: GSE11524

ID:: 200011524

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 33182.

Sickle cell disease: platelets

Analysis of platelets from patients with sickle cell disease. Sickle cell disease patients exhibit increased activation of platelets. Results provide insight into the molecular basis of platelet dysfunction in sickle cell disease.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL570
Series:: GSE11524
30 Samples

Download data: CEL

DataSet

Accession:: GDS3318

ID:: 3318

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...