GEO DataSets

(Submitter supplied) Housekeeping genes (HKG) are constitutively expressed in all tissues while tissue-enriched genes (TEG) are expressed at a much higher level in a single tissue type than in others. HKGs serve as valuable experimental controls in gene and protein expression experiments, while TEGs tend to represent distinct physiological processes and are frequently candidates for biomarkers or drug targets. The genomic features of these two groups of genes expressed in opposing patterns may shed light on the mechanisms by which cells maintain basic and tissue-specific functions. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

26 related Platforms

564 Samples

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(Submitter supplied) Alternative pre-messenger RNA splicing impacts development, physiology, and disease, but its regulation in humans is not well understood, partially due to the limited scale to which the expression of specific splicing events has been measured. We generated the first genome-scale expression compendium of human alternative splicing events using custom whole-transcript microarrays monitoring expression of 24,426 mutually exclusive alternative splicing event pairs in 48 diverse human samples. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

17 related Platforms

813 Samples

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(Submitter supplied) Oligonucleotide array on glass. Microarray pattern generation. We downloaded genome and transcript sequences from the National Center for Biotechnology Information on January 8, 2003. We aligned RefSeq, mRNA, EST57 and patent transcripts to the genome using sim458 and identified all exons and exon-exon junctions. We also aligned mouse transcripts to the human genome to identify possible splice forms not yet present in human transcript databases59. more...

Organism:

Homo sapiens

2 Series

49 Samples

Download data: PSL