GSM3146465[Accession] - GEO DataSets

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Items: 4

Select item 2001223851.

Epigenome regulation during epidermal lineage commitment

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL18573 GPL11154
61 Samples

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Series

Accession:: GSE122385

ID:: 200122385

PubMed Full text in PMC Similar studies

Select item 2001082482.

Epigenome regulation during epidermal lineage commitment [ATAC-seq, RNA-seq]

(Submitter supplied) Recent advances in human pluripotent stem cell (hPSC) technology provide a unique resource for skin tissue replacement, but the detailed understanding of regulatory mechanisms limits standardization and broad clinical application. Here, we interrogate chromatin accessibility and transcriptome dynamics during hPSC-derived epidermal differentiation, and discover two critical transition periods: surface ectoderm initiation and keratinocyte maturation. more...