GSM5380722[Accession] - GEO DataSets

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Items: 4

Select item 2001781351.

Treg cells and Treg-specific deletion of Blimp1

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array; Expression profiling by high throughput sequencing

Platforms:: GPL28581 GPL21103 GPL29428
17 Samples

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Series

Accession:: GSE178135

ID:: 200178135

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001781322.

Gene expression profile of effector Treg cells isolated from spleens and tumors of tumor-bearing mice

(Submitter supplied) A majority of effector Treg cells (eTregs) that are abundant in many types of tumors are marked by the expression of Blimp1. However, the specific impact of Blimp1+ eTregs on, and mechanisms of action within, tumors remain unknown. To better understand the role of Blimp1 in the regulation of eTreg function in the tumor immunity, we profiled the differential gene expression in Blimp1-deficient eTregs compared to WT control eTregs from tumor-bearing mice.