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Items: 4

1.

Gene expression data from temporal cortex of young adult, old and AD-like Microcebus murinus

(Submitter supplied) Aging is the primary risk factor of neurodegenerative disorders such as Alzheimer's disease (AD). However, the molecular events occurring during brain aging are extremely complex and still largely unknown. For a better understanding of these age-associated modifications, animal models as close as possible to humans are needed. We thus analyzed the transcriptome of the temporal cortex of the primate Microcebus murinus using human oligonucleotide microarrays (Affymetrix). more...
Organism:
Homo sapiens; Microcebus murinus
Type:
Expression profiling by array
Dataset:
GDS4128
Platform:
GPL570
18 Samples
Download data: CEL, CHP
Series
Accession:
GSE21779
ID:
200021779
2.
Full record GDS4128

Model of cerebral aging and Alzheimer's disease: temporal cortex

Analysis of temporal cortex of young adult, old healthy, and Alzheimer’s disease (AD-like) animals. AD-like animals presented ß-amyloid plaques and cortical atrophy, which are signs of AD in humans. Results provided insight into molecular basis of physiological versus pathological brain aging.
Organism:
Homo sapiens; Microcebus murinus
Type:
Expression profiling by array, count, 2 age, 2 disease state, 2 gender sets
Platform:
GPL570
Series:
GSE21779
18 Samples
Download data: CEL, CHP
3.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5664 Series
61 Related Platforms
171691 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570
4.

Temporal Cortex_AD_F2

Organism:
Microcebus murinus
Source name:
Temporal cortex from old Microcebus murinus, "AD-like", female (2)
Platform:
GPL570
Series:
GSE21779
Dataset:
GDS4128
Download data: CEL, CHP
Sample
Accession:
GSM542559
ID:
300542559
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