GEO DataSets

(Submitter supplied) MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate gene expression post-transcriptionally. They play a critical role in developmental and physiological processes and have been implicated in the pathogenesis of several diseases including cancer. To identify miRNA signatures associated with different stages of neoplastic development, we examined the expression profile of 776 primate miRNAs in the following cells: primary African green monkey kidney (pAGMK) cells; spontaneously immortalized, non-tumorigenic, low-passage VERO cells (10-87 LP); tumorigenic, high-passage VERO cells (10-87 HP); and a cell line (10-87 T) derived from a 10-87 HP cell tumor xenograft in athymic nude mice. more...

Organism:

Lemur catta; Lagothrix lagotricha; Macaca nemestrina; Homo sapiens; Pan paniscus; Chlorocebus aethiops; Macaca mulatta; Pan troglodytes; Pongo pygmaeus; Ateles geoffroyi; Gorilla gorilla; Saguinus labiatus

Type:

Non-coding RNA profiling by array

Platform:

GPL10649

9 Samples

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(Submitter supplied) Primates miRNA microarray with 100% coverage of mature miRNAs listed in miRBase version 10.0 Protocol: Arrays are made based µParaflo microfluidic technology (Atactic Technologies). On the µParaflo microfluidic chip, each detection probe consists of a chemically modified nucleotide coding segment complementary to target microRNA (from miRBase, http://www.mirbase.org) or other RNA (control or customer defined sequences) and a spacer segment of polyethylene glycol to extend the coding segment away from the substrate. more...

Organism:

Lemur catta; Ateles geoffroyi; Lagothrix lagotricha; Macaca mulatta; Macaca nemestrina; Gorilla gorilla; Pan paniscus; Pan troglodytes; Pongo pygmaeus; Homo sapiens; Saguinus labiatus

1 Series

9 Samples

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