GSM65292[Accession] - GEO DataSets

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Items: 4

Select item 2000030131.

Actions of tamoxifen in the uterus and its molecular effectors in endometrial carcinogenesis.

(Submitter supplied) The molecular explanation for tamoxifen serving as a breast cancer treatment but displaying partial estrogenic in the uterus is not known. Previously, we reported that differential promoter context and cofactor recruitment contribute to the tissue specificity of tamoxifen. Here, we investigated the genomic basis for the partial oestrogenic activity of tamoxifen in the endometrium. We showed that tamoxifen not only affects the rate of transcription of oestrogen target genes but also targets a unique set of genes. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS1510 GDS3604
Platforms:: GPL8300 GPL91
18 Samples

Download data: CEL, EXP

Series

Accession:: GSE3013

ID:: 200003013

Select item 15102.

Tamoxifen effect on normal endometrial epithelium

Analysis of normal endometrial epithelial cells following treatment with oestrogen or tamoxifen (TMX). Results provide insight into the molecular basis of the association of TMX treatment of breast cancer with an increased incidence of endometrial cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 agent sets

Platform:: GPL8300
Series:: GSE3013
6 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS1510

ID:: 1510

Select item 1000083003.

[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Based on this UniGene build and associated annotations, the HG-U95Av2 array represents approximately 10,000 full-length genes. more...