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Items: 4

1.

Multiplex profiling of developmental enhancers with quantitative, single-cell expression reporters [bulkMPRA_devCRE_mEBs]

(Submitter supplied) The inability to scalably and precisely measure the cell-type-specific activity of developmental enhancers is a bottleneck in genomics. To address this, we developed a “dual RNA”' system that decouples the detection and quantification tasks inherent to multiplex single-cell reporter assays. Together with RNA barcode circularization, the resulting single-cell quantitative expression reporters (scQers) facilitate the robust detection of which reporter(s) are present in which single cells, thereby providing high contrast readouts analogous to classic in situ assays but entirely from sequencing. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL19057 GPL30172
80 Samples
Download data: TXT
Series
Accession:
GSE217679
ID:
200217679
2.

Multiplex profiling of developmental enhancers with quantitative, single-cell expression reporters

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Escherichia coli; Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
7 related Platforms
368 Samples
Download data
Series
Accession:
GSE217690
ID:
200217690
3.

NextSeq 2000 (Mus musculus)

Platform
Accession:
GPL30172
ID:
100030172
4.

bulk_MPRA_mEB_series_mBC_repA_d20_DNA

Organism:
Mus musculus
Source name:
WD44 (mouse embryonic stem cells)
Platform:
GPL30172
Series:
GSE217679 GSE217690
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Sample
Accession:
GSM6724862
ID:
306724862
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