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Items: 4

1.

Expression data of A375 melanoma cells after DMSO or MLN4924 treatment from 1 hour to 24 hour

(Submitter supplied) Microarrays were used to determine the change in gene expression of genes involved in the CDT1/NAE pathway
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4819
Platform:
GPL570
30 Samples
Download data: CEL
Series
Accession:
GSE30531
ID:
200030531
2.
Full record GDS4819

Inhibitor of NEDD8-activating enzyme MLN4924 effect on melanoma cell line

Analysis of A375 melanoma cells treated with small molecule MLN4924 for up to 24 hrs. MLN4924 selectively inhibits Nedd8-activating enzyme resulting in inactivation of the entire family of Cullin-RING ubiquitin ligases. Results provide insight into the molecular basis of MLN4924-induced cell death.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 5 time sets
Platform:
GPL570
Series:
GSE30531
30 Samples
Download data: CEL
3.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5668 Series
61 Related Platforms
174546 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570
4.

650nM MLN4924 after 1hr, replicate 1

Organism:
Homo sapiens
Source name:
Cell culture of Melanoma Cell Line - A375
Platform:
GPL570
Series:
GSE30531
Dataset:
GDS4819
Download data: CEL
Sample
Accession:
GSM757128
ID:
300757128
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