GSM7780196[Accession] - GEO DataSets

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Items: 4

Select item 2002431841.

ETS1, a target gene of the EWSR1::FLI1 fusion oncoprotein, regulates the expression of the focal adhesion protein TENSIN3

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:: GPL30173
63 Samples

Download data: BED, BIGWIG, NARROWPEAK

Series

Accession:: GSE243184

ID:: 200243184

PubMed Full text in PMC Similar studies

Select item 2002431712.

EWSR1::FLI1 fusion oncoproteins’ regulation of ETS1 (ChIP-seq)

(Submitter supplied) Ewing sarcomas harbor few mutations beyond the chromosomal translocation that initiates disease and the mechanistic basis for the metastasis of these tumors remains poorly understood. The epigenome of Ewing sarcoma (EWS) cells reflects the regulatory state of genes associated with the DNA binding activity of the fusion oncoproteins EWSR1::FLI1 or EWSR1::ERG. In this study, we examined the repressive activities of the EWSR1::FLI1/ERG fusion oncoproteins. more...