GSM7884818[Accession] - GEO DataSets

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Items: 4

Select item 2002471991.

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Macaca mulatta; Homo sapiens; Mus musculus; Rattus

Type:: Methylation profiling by genome tiling array; Expression profiling by high throughput sequencing

Platforms:: GPL24247 GPL32543
60 Samples

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Series

Accession:: GSE247199

ID:: 200247199

PubMed Full text in PMC Similar studies

Select item 2002471792.

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation [Array]

(Submitter supplied) Partial reprogramming by cyclic short-term expression of Yamanaka factors holds promise for shifting cells to younger states and consequently delaying the onset of many diseases of aging. However, the delivery of transgenes and potential risk of teratoma formation present challenges for in vivo applications. Recent advances include the use of cocktails of compounds to reprogram somatic cells, but the characteristics and mechanisms of partial cellular reprogramming by chemicals remain unclear. more...