GSM8309036[Accession] - GEO DataSets

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Items: 4

Select item 2002692351.

A Constitutive Heterochromatic Region Shapes Genome Organization and Impacts Gene Expression in Neurospora crassa

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Neurospora crassa

Type:: Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing

Platforms:: GPL20705 GPL26551
23 Samples

Download data: BEDGRAPH, BIGWIG, H5, TXT

Series

Accession:: GSE269235

ID:: 200269235

PubMed Full text in PMC Similar studies

Select item 2002692302.

A Constitutive Heterochromatic Region Shapes Genome Organization and Impacts Gene Expression in Neurospora crassa [RNA-Seq]

(Submitter supplied) Genome organization is essential for proper function, including gene expression. In metazoan genome organization, chromatin loops and Topologically Associated Domains (TADs) facilitate local gene clustering, while chromosomes form distinct nuclear territories characterized by compartmentalization of silent heterochromatin at the nuclear periphery and active euchromatin in the nucleus center. A similar hierarchical organization occurs in the fungus Neurospora crassa where its seven chromosomes form a Rabl conformation, where heterochromatic centromeres and telomeres independently cluster at the nuclear membrane, while interspersed heterochromatic loci in Neurospora aggregate across megabases of linear genomic distance for forming TAD-like structures. more...