GSM998413[Accession] - GEO DataSets

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Items: 3

Select item 2000406331.

Oral Benzo[a]pyrene in Cyp1a1/1b1(-/-) Double-Knockout Mice: Microarray Analysis During Squamous Cell Carcinoma Formation in Preputial Gland Duct

(Submitter supplied) Benzo[a]pyrene (BaP) is a prototypical polycyclic aromatic hydrocarbon (PAH) found in combustion processes. Cytochrome P450 1A1 and 1B1 enzymes (CYP1A1, CYP1B1) and other enzymes can activate PAHs to reactive oxygenated intermediates involved in mutagenesis and tumor initiation; also, CYP1 enzymes can detoxify PAHs. Cyp1(+/+) wild-type (WT) and Cyp1b1(-/-) knockout mice receiving oral BaP (12.5 mg/kg/day) remain healthy for >12 months. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11078
30 Samples

Download data: CEL

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Accession:: GSE40633

ID:: 200040633

Select item 1000110782.

[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [CDF: MoGene10stv1_Mm_ENTREZG_13]

(Submitter supplied) see manufacturer's web site This is identical to GPL6246 but a custom cdf environment was used to extract data. ANNOTATION: chip library files are provided as supplementary files below, and can be downloaded at: http://brainarray.mbni.med.umich.edu/Brainarray/Database/CustomCDF/CDF_download.asp as Package name mogene10stv1mmentrezg. vers13 july 6 2010.