GEO DataSets

(Submitter supplied) RNA-seq data for Sulfolobus islandicus REY15A Δcbp1 strain and the parental strain E234

Organism:

Sulfolobus islandicus REY15A

Type:

Expression profiling by high throughput sequencing

Platform:

GPL33142

4 Samples

Download data: BW, TXT

(Submitter supplied) To investigate the putative functions of the ssDNA binding proteins SisSSB and SisDBP in DNA replication, DNA repair and DNA damage response, we constructed Sisssb and Sisdbp deletion mutants of S. islandicus.

Organism:

Sulfolobus islandicus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32733

9 Samples

Download data: TXT

(Submitter supplied) To investigate the function of the FHA protein SisFha in the regulation of gene transcription during DNA damage response, we constructed Sisfha deletion mutant of S. islandicus and treated with NQO.

Organism:

Sulfolobus islandicus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32733

12 Samples

Download data: TXT

(Submitter supplied) We used one of the RNA-DNA proximity ligation approaches, RedC, for the analysis of an RNA-DNA interactome of microbial cells. We assess the distribution of main RNA types — mRNA, tRNA and rRNA — along the genomes of E.coli, B.subtilis, and thermophilic archaea T. adornatum.

Organism:

Bacillus subtilis; Escherichia coli; Thermofilum adornatum

Type:

Other

Platforms:

GPL32512 GPL30886 GPL25368

6 Samples

Download data: TSV

(Submitter supplied) A Type II VapB14 Antitoxin regulates biofilm dispersal in the archaeal thermoacidophile Sulfolobus acidocaldarius, not only through traditional Toxin neutralization but also through noncanonical transcriptional regulation. Type II VapC Toxins are ribonucleases that are neutralized by their proteinaceous cognate Type II VapB Antitoxin. VapB Antitoxins have a flexible tail at their C-terminus that covers the Toxin’s active site neutralizing its activity. more...

Organism:

Sulfolobus acidocaldarius; Sulfolobus acidocaldarius DSM 639

Type:

Expression profiling by array

Platform:

GPL33204

4 Samples

Download data: GPR, TXT

(Submitter supplied) CRISPR arrays form the physical memory of CRISPR adaptive immune systems by incorporating foreign DNA as spacers that are often AT-rich and derived from viruses. As promoter elements such as the TATA-box are AT-rich, CRISPR arrays are prone to harbouring cryptic promoters. Sulfolobales harbor extremely long CRISPR arrays spanning several kilobases, a feature that is accompanied by the CRISPR-specific transcription factor Cbp1. more...

Organism:

Saccharolobus solfataricus P2; Sulfolobus islandicus LAL14/1; Sulfolobus islandicus REY15A

Type:

Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

7 related Platforms

48 Samples

Download data: BW

(Submitter supplied) Chromatin proteins competes with the transcription machinery for access to genomic DNA and suppress cryptic promoters. CRISPR arrays form the physical memory of CRISPR adaptive immune systems. The incorporation of virus-derived AT-rich DNA into CRISPR arrays renders them prone to harbouring cryptic promoters. Sulfolobales feature extremely long CRISPR arrays spanning several kilobases as well as a CRISPR-specific chromatin protein termed Cbp1. more...

Organism:

Saccharolobus solfataricus P2

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platforms:

GPL33185 GPL33184

4 Samples

Download data: BW

(Submitter supplied) Chromatin proteins competes with the transcription machinery for access to genomic DNA and suppress cryptic promoters. CRISPR arrays form the physical memory of CRISPR adaptive immune systems. The incorporation of virus-derived AT-rich DNA into CRISPR arrays renders them prone to harbouring cryptic promoters. Sulfolobales feature extremely long CRISPR arrays spanning several kilobases as well as a CRISPR-specific chromatin protein termed Cbp1. more...

Organism:

Sulfolobus islandicus LAL14/1

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL32880

12 Samples

Download data: BW

(Submitter supplied) Chromatin proteins competes with the transcription machinery for access to genomic DNA and suppress cryptic promoters. CRISPR arrays form the physical memory of CRISPR adaptive immune systems. The incorporation of virus-derived AT-rich DNA into CRISPR arrays renders them prone to harbouring cryptic promoters. Sulfolobales feature extremely long CRISPR arrays spanning several kilobases as well as a CRISPR-specific chromatin protein termed Cbp1. more...

Organism:

Saccharolobus solfataricus P2

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL33184

4 Samples

Download data: BW

(Submitter supplied) Chromatin proteins competes with the transcription machinery for access to genomic DNA and suppress cryptic promoters. CRISPR arrays form the physical memory of CRISPR adaptive immune systems. The incorporation of virus-derived AT-rich DNA into CRISPR arrays renders them prone to harbouring cryptic promoters. Sulfolobales feature extremely long CRISPR arrays spanning several kilobases as well as a CRISPR-specific chromatin protein termed Cbp1. more...

Organism:

Sulfolobus islandicus REY15A

Type:

Other

Platform:

GPL33183

4 Samples

Download data: BW

(Submitter supplied) Chromatin proteins competes with the transcription machinery for access to genomic DNA and suppress cryptic promoters. CRISPR arrays form the physical memory of CRISPR adaptive immune systems. The incorporation of virus-derived AT-rich DNA into CRISPR arrays renders them prone to harbouring cryptic promoters. Sulfolobales feature extremely long CRISPR arrays spanning several kilobases as well as a CRISPR-specific chromatin protein termed Cbp1. more...

Organism:

Sulfolobus islandicus REY15A

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platforms:

GPL23498 GPL33142 GPL24667

20 Samples

Download data: BW

(Submitter supplied) Cell cycle regulation is of paramount importance for all forms of life. Here we report that a conserved and essential cell cycle-specific transcription factor (designated as aCcr1) and its viral homologs control cell division in Sulfolobales. We show that the transcription level of accr1 reaches peak during active cell division (D-phase) subsequent to the expression of CdvA, an archaea-specific cell division protein. more...

Organism:

Sulfolobus islandicus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32733

18 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Sulfolobus islandicus

Type:

Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL32733

9 Samples

Download data: BW

(Submitter supplied) Cell cycle regulation is of paramount importance for all forms of life. Here we report that a conserved and essential cell cycle-specific transcription factor (designated as aCcr1) and its viral homologs control cell division in Sulfolobales. We show that the transcription level of accr1 reaches peak during active cell division (D-phase) subsequent to the expression of CdvA, an archaea-specific cell division protein. more...

Organism:

Sulfolobus islandicus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32733

6 Samples

Download data: XLS

(Submitter supplied) Cell cycle regulation is of paramount importance for all forms of life. Here we report that a conserved and essential cell cycle-specific transcription factor (designated as aCcr1) and its viral homologs control cell division in Sulfolobales. We show that the transcription level of accr1 reaches peak during active cell division (D-phase) subsequent to the expression of CdvA, an archaea-specific cell division protein. more...

Organism:

Sulfolobus islandicus

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL32733

3 Samples

Download data: BW

(Submitter supplied) To identify putative target genes in S. islandicus LAL14/1 of the viral transcriptional regulator SIRV2 gp21

Organism:

Sulfolobus islandicus LAL14/1

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32880

12 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Cavia porcellus; Ignicoccus hospitalis; Capra hircus; Homo sapiens; Mus musculus

Type:

Genome variation profiling by genome tiling array

7 related Platforms

56 Samples

Download data: CEL, CYCHP, OSCHP

(Submitter supplied) Pediatric nodal marginal zone lymphoma (PNMZL) is an unusual and poorly understood primary B-cell nodal neoplasms. Patients are predominantly young males presenting with localized disease. The tumor shows overlapping morphological features with pediatric-type follicular lympgoma. The alterations involved in the pathogenesis of PNMZL are not known.

Organism:

Homo sapiens; Cavia porcellus; Ignicoccus hospitalis; Mus musculus; Capra hircus

Type:

Genome variation profiling by genome tiling array

6 related Platforms

53 Samples

Download data: CEL, OSCHP

(Submitter supplied) Chromosome conformation capture (3C) technologies have identified topologically associating domains (TADs) and larger A/B compartments as two salient structural features of eukaryotic chromosomes. These structures are sculpted by the combined actions of transcription and structural maintenance of chromosomes (SMC) superfamily proteins. Bacterial chromosomes fold into TAD-like chromosomal interaction domains (CIDs) but do not display A/B compartment-type organization. more...

Organism:

Sulfolobus islandicus; Sulfolobus acidocaldarius

Type:

Expression profiling by high throughput sequencing; Other

Platforms:

GPL26274 GPL26275

31 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Saccharolobus solfataricus

Type:

Expression profiling by high throughput sequencing; Other

Platforms:

GPL27060 GPL28445

9 Samples

Download data: WIG