GEO DataSets

(Submitter supplied) Polyamines, crucial molecules involved in cell proliferation and growth, play a pivotal role in cancer development and progression. Within the tumor microenvironment, macrophages, key components of the immune system, exhibit a complex relationship with polyamines. Evidence suggests that polyamines can modulate macrophage polarization, influencing their functional phenotypes. Here, we detected the gene DNA methylation changes in spermine-stimulated human macrophages isolated from PBMCs and TAMs.

Organism:

Leptospira interrogans; Rickettsia typhi; Mycobacterium tuberculosis variant bovis; Mycobacterium tuberculosis; Mycobacterium tuberculosis variant microti; Mycobacterium canetti; Orthohantavirus seoulense; Yersinia pseudotuberculosis; Rickettsia prowazekii; Bartonella quintana; Mycobacterium avium; Homo sapiens; Streptobacillus moniliformis; Bartonella henselae; Francisella tularensis subsp. tularensis; Francisella tularensis subsp. holarctica; Yersinia enterocolitica; Toxoplasma gondii; Salmonella enterica subsp. enterica serovar Typhimurium; Mammarenavirus choriomeningitidis; Orthohantavirus puumalaense; Campylobacter jejuni; Francisella tularensis subsp. novicida; Yersinia pestis; Staphylococcus aureus; Mycobacterium avium subsp. paratuberculosis; Cowpox virus; Escherichia coli O157:H7; Francisella tularensis subsp. mediasiatica; Paslahepevirus balayani

Type:

Methylation profiling by array

Platform:

GPL21445

4 Samples

Download data: IDAT, TXT

(Submitter supplied) A microarray was developed to screen rodent samples for pathogens of zoonotic importance In the work described here, a homologue to Yersinia pestis was found in rodent samples after screening with the microarray

Organism:

Leptospira interrogans; Francisella tularensis subsp. novicida; Yersinia pseudotuberculosis; Mycobacterium avium subsp. paratuberculosis; Mycobacterium tuberculosis; Mus musculus; Streptobacillus moniliformis; Bartonella henselae; Francisella tularensis subsp. tularensis; Paslahepevirus balayani; Campylobacter jejuni; Yersinia pestis; Mycobacterium tuberculosis variant microti; Rattus rattus; Mycobacterium canetti; Francisella tularensis subsp. mediasiatica; Mammarenavirus choriomeningitidis; Orthohantavirus puumalaense; Orthohantavirus seoulense; Bartonella quintana; Staphylococcus aureus; Mycobacterium avium; Rattus norvegicus; Cowpox virus; Escherichia coli O157:H7; Francisella tularensis subsp. holarctica; Yersinia enterocolitica; Rickettsia prowazekii; Rickettsia typhi; Mycobacterium tuberculosis variant bovis; Toxoplasma gondii; Apodemus sylvaticus; Salmonella enterica subsp. enterica serovar Typhimurium

Type:

Genome variation profiling by array

Platform:

GPL21445

65 Samples

Download data: TXT

(Submitter supplied) The development of rapid and sensitive assays capable of detecting a wide range of infectious agents is critical for the effective diagnosis of diseases that have multiple etiologies. In recent years, many microarray-based diagnostics have been developed to identify viruses present in clinical specimens in a highly parallel fashion. Unfortunately, the rate of development of algorithms to interpret data generated from such platforms has not been commensurate. more...

Organism:

dengue virus type 4; La Crosse virus; Rift Valley fever virus; Toscana virus; Kyasanur Forest disease virus; Orthohantavirus seoulense; dengue virus type 1; dengue virus type 3; Ebola virus - Gabon (1994-1997); Sudan ebolavirus; Ngari virus; Mammarenavirus amapariense; Mammarenavirus mopeiaense; Mammarenavirus tacaribeense; Orthohantavirus hantanense; Orthonairovirus haemorrhagiae; dengue virus type 2; Yellow fever virus; Filoviridae; Omsk hemorrhagic fever virus; California encephalitis virus; Rocio virus; Zaire ebolavirus; Reston ebolavirus; Lake Victoria marburgvirus - Angola2005; Mammarenavirus brazilense; Mammarenavirus ippyense; Flaviviridae; Arenaviridae; unidentified; Peribunyaviridae; Mammarenavirus juninense; Mammarenavirus choriomeningitidis; Mammarenavirus guanaritoense; Mammarenavirus lassaense; Mammarenavirus machupoense; Mammarenavirus praomyidis; Orthohantavirus puumalaense

Type:

Other

Platform:

GPL10345

110 Samples

Download data: GPR

(Submitter supplied) Oligonucleotides were purchased as 3′-amino-modified oligos from Metabion (Martinsried, Germany) and applied at a final concentration of 10 μM in Spotting Buffer 1 (Quantifoil Micro Tools, Jena, Germany). Arrays were spotted using a Microgrid II spotting machine (BioRobotics Inc., Cambridge, UK) according to the instructions of the manufacturer and assembled into ArrayStrips. Each oligonucleotide probe was replicated two-fold on the array. more...

Organism:

Leptospira interrogans; Campylobacter jejuni; Francisella tularensis subsp. novicida; Yersinia enterocolitica; Yersinia pestis; Yersinia pseudotuberculosis; Rickettsia prowazekii; Rickettsia typhi; Bartonella quintana; Staphylococcus aureus; Mycobacterium avium; Mycobacterium tuberculosis variant bovis; Mycobacterium avium subsp. paratuberculosis; Mycobacterium tuberculosis; Mycobacterium tuberculosis variant microti; Toxoplasma gondii; Cowpox virus; Streptobacillus moniliformis; Bartonella henselae; Mycobacterium canetti; Escherichia coli O157:H7; Salmonella enterica subsp. enterica serovar Typhimurium; Francisella tularensis subsp. tularensis; Francisella tularensis subsp. holarctica; Francisella tularensis subsp. mediasiatica; Paslahepevirus balayani; Mammarenavirus choriomeningitidis; Orthohantavirus puumalaense; Orthohantavirus seoulense

2 Series

69 Samples

Download data