GEO DataSets

(Submitter supplied) We report a novel mechanism of gene origination in the segmented negative sense viruses (sNSVs), including IAV and LASV. During replication, these viruses use "snatched" host caps to prime their own transcription (cap-snatching). We show that a proportion of cap-snatched host sequences contain translational start codons (AUGs), that are recognized by the host ribosome. This allows for the translation of host and viral “untranslated regions” (UTRs) to create N-terminally extended viral proteins or entirely novel polypeptides by genetic overprinting.

Organism:

Mammarenavirus lassaense

Type:

Other

Platform:

GPL28344

1 Sample

Download data: XLSX

(Submitter supplied) Emerging viruses are usually endemic to tropical and sub-tropical regions of the world, but increased global travelling, climate changes and changes in lifestyle are believed to contribute to the spread of these viruses into new regions. For many of them, the disease symptoms are similar to each other, as well as to other more common diseases, making them difficult to diagnose. A rapid identification will help to decide about specific treatment and appropriate case management. more...

Organism:

Cowpox virus; Orf virus; dengue virus type 1; dengue virus type 3; Japanese encephalitis virus; Tick-borne encephalitis virus; sandfly fever Sicilian virus; Marburgvirus; Sandfly fever Naples virus; Orthohantavirus hantanense; Orthonairovirus haemorrhagiae; Eastern equine encephalitis virus; Dengue virus; synthetic construct; Mammarenavirus lassaense; Orthohantavirus dobravaense; Orthohantavirus puumalaense; Monkeypox virus; dengue virus type 4; West Nile virus; Rift Valley fever virus; Chikungunya virus; Human poliovirus sp.; Hepacivirus hominis; Orthohantavirus seoulense; Orthohantavirus sinnombreense; dengue virus type 2; Yellow fever virus; Toscana virus; Usutu virus; Zaire ebolavirus

Type:

Other

Platform:

GPL18370

64 Samples

Download data: PAIR

(Submitter supplied) Emerging viruses are usually endemic to tropical and sub-tropical regions of the world, but increased global travelling, climate changes and changes in lifestyle are believed to contribute to the spread of these viruses into new regions. For many of them, the disease symptoms are similar to each other, as well as to other more common diseases, making them difficult to diagnose. A rapid identification will help to decide about specific treatment and appropriate case management. more...

Organism:

Zaire ebolavirus; Hepacivirus hominis; Mammarenavirus lassaense; Monkeypox virus; West Nile virus; Yellow fever virus; Rift Valley fever virus; Toscana virus; sandfly fever Sicilian virus; Chikungunya virus; Human poliovirus sp.; Sandfly fever Naples virus; Orthohantavirus hantanense; Orthohantavirus seoulense; Orthohantavirus sinnombreense; Eastern equine encephalitis virus; dengue virus type 2; Dengue virus; synthetic construct; Usutu virus; Orthohantavirus puumalaense; Orthonairovirus haemorrhagiae; Cowpox virus; Orf virus; Marburgvirus; Orthohantavirus dobravaense

Type:

Other

Platform:

GPL17919

42 Samples

Download data: PAIR

(Submitter supplied) The development of rapid and sensitive assays capable of detecting a wide range of infectious agents is critical for the effective diagnosis of diseases that have multiple etiologies. In recent years, many microarray-based diagnostics have been developed to identify viruses present in clinical specimens in a highly parallel fashion. Unfortunately, the rate of development of algorithms to interpret data generated from such platforms has not been commensurate. more...

Organism:

dengue virus type 1; dengue virus type 3; Ebola virus - Gabon (1994-1997); Sudan ebolavirus; Ngari virus; Mammarenavirus amapariense; Mammarenavirus mopeiaense; Mammarenavirus tacaribeense; Orthohantavirus hantanense; Orthonairovirus haemorrhagiae; dengue virus type 4; La Crosse virus; Rift Valley fever virus; Toscana virus; Kyasanur Forest disease virus; Orthohantavirus seoulense; Flaviviridae; Arenaviridae; unidentified; Peribunyaviridae; Mammarenavirus juninense; Mammarenavirus choriomeningitidis; Mammarenavirus guanaritoense; Mammarenavirus lassaense; Mammarenavirus machupoense; Mammarenavirus praomyidis; Orthohantavirus puumalaense; dengue virus type 2; Yellow fever virus; Filoviridae; Omsk hemorrhagic fever virus; California encephalitis virus; Rocio virus; Zaire ebolavirus; Reston ebolavirus; Lake Victoria marburgvirus - Angola2005; Mammarenavirus brazilense; Mammarenavirus ippyense

Type:

Other

Platform:

GPL10345

110 Samples

Download data: GPR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Vesicular stomatitis Indiana virus; Human adenovirus E4; Echovirus E18; artificial sequences; Influenza A virus (A/Texas/36/1991(H1N1)); Lassa virus Josiah; Chlorocebus aethiops; Homo sapiens; Human alphaherpesvirus 1; Zaire ebolavirus; SARS coronavirus Tor2; Viruses; West Nile virus

Type:

Expression profiling by array

Platforms:

GPL10319 GPL10320

40 Samples

Download data: TXT

(Submitter supplied) Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery assays is a challenging task. Target template concentration, nucleic acid integrity, and host nucleic acid composition can each have a profound effect on signal distribution. Exploratory analysis of fluorescent signal distribution in clinical samples has revealed deviations from normality, suggesting that distribution-free approaches should be applied. more...

Organism:

Viruses; West Nile virus; Lassa virus Josiah; Chlorocebus aethiops; Human alphaherpesvirus 1; Human adenovirus E4; Zaire ebolavirus; SARS coronavirus Tor2; Vesicular stomatitis Indiana virus; Echovirus E18; Influenza A virus (A/Texas/36/1991(H1N1))

Type:

Expression profiling by array

Platform:

GPL10320

11 Samples

Download data: TXT