The pioneer transcription factor Zelda facilitates the exit from regeneration and restoration of patterning in Drosophila - - GEO DataSets

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The pioneer transcription factor Zelda facilitates the exit from regeneration and restoration of patterning in Drosophila

(Submitter supplied) For a damaged tissue to regenerate, the injured site must repair the wound, proliferate, and restore the correct patterning and cell types. We found that Zelda, a pioneer transcription factor largely known for its role in embryonic zygotic genome activation, is dispensable for normal wing development but crucial for wing disc patterning during regeneration. Impairing Zelda function during disc regeneration resulted in adult wings with a plethora of cell fate errors, affecting the veins, margins, and posterior compartment identity. more...

Organism:: Drosophila melanogaster

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL25244
8 Samples

Download data: BED, BIGWIG, NARROWPEAK

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Accession:: GSE268674

ID:: 200268674

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