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Items: 3

1.

Screening for Epigenetically Masked Genes in Colorectal Cancer using 5-aza-2’-deoxycytidine treatment, Microarray and Gene Expression Profile

(Submitter supplied) Unearthing of silenced genes in colorectal cancer (CRC) is of great importance. We employed oligonucleotide microarray to find changes in global gene expression of five CRC cell lines. These were analyzed before and after treatment with the 5-aza-2'-Deoxycitidine. Expression of the responding genes was integrated with gene expression profiling generated by microarray analysis of matched colorectal tissue samples. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS4382 GDS4397
Platform:
GPL570
44 Samples
Download data: CEL
Series
Accession:
GSE32323
ID:
200032323
2.
Full record GDS4397

5-aza-2’-deoxycytidine effect on colorectal cancer cell lines

Analysis of colorectal cancer (CRC) cell lines treated with 5-aza-2’-deoxycytidine (5-aza-dC). 5-aza-dC, a DNA methylation inhibitor, was used to reactivate silenced genes in the CRC cell lines. Results provide insight into the molecular mechanisms underlying epigenetic alterations in CRC.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 5 cell line sets
Platform:
GPL570
Series:
GSE32323
10 Samples
Download data: CEL
DataSet
Accession:
GDS4397
ID:
4397
3.
Full record GDS4382

Colorectal cancer tumors

Analysis of paired colorectal cancer (CRC) tumors and adjacent non-cancerous tissues. Colorectal cancer is a worldwide public health problem. Results provide insight into the molecular mechanisms underlying CRC carcinogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 17 individual, 2 tissue sets
Platform:
GPL570
Series:
GSE32323
34 Samples
Download data: CEL
DataSet
Accession:
GDS4382
ID:
4382
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