GEO DataSet Links for BioProject (Select 196872) - GEO DataSets

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Items: 2

Select item 2000460101.

The gene expression change of RNF31 depletion in MCF-7 cells

(Submitter supplied) RNF31 is atypical E3 ligase, which is highly expressed in human breast cancers. In order to understand the effect of RNF31 depletion effect in breast cancers, we knocked down the expression of RNF31 in MCF-7 cells. We aim to find the significantly changed pathways and cell biology behavior.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5371
Platform:: GPL6480
7 Samples

Download data: TXT

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Accession:: GSE46010

ID:: 200046010

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 53712.

Atypical ubiquitin ligase RNF31 depletion effect on ER-alpha positive breast cancer cell line

Analysis of MCF-7 breast cancer cells depleted for RNF31. RNF31 is an atypical E3 ubiquitin ligase. MCF-7 is an estrogen receptor (ER) alpha positive cell line. Results provide insight into the role of RNF31 in the ER-alpha stimulated proliferation of breast cancer cells.