GEO DataSet Links for BioProject (Select 217449) - GEO DataSets

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Items: 2

Select item 2000504141.

Genome-wide expression analysis of VprBP knockdown in DU145 cells

(Submitter supplied) VprBP has been implicated in transcriptionally silent chromatin formation and cell cycle regulation, but the molecular basis underlying such effects remains unclear. To investigate the role of VprBP on gene regulation, genme-wide gene expression analysis is carried out in DU145 cells expressing either control shRNA or VprBP shRNA.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4829
Platform:: GPL10558
4 Samples

Download data: TXT

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Accession:: GSE50414

ID:: 200050414

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 48292.

VprBP depletion effect on prostate cancer cell line

Analysis of DU145 prostate cancer cells depleted for Vpr binding protein (VPRBP). VPRBP knockdown decreases histone H2A threonine 120 (H2AT120) phosphorylation and impairs the viability of DU145 cells. Results provide insight into the role of VprBP in regulating gene transcription.