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A G-protein-coupled receptor modulates gametogenesis via PKG-mediated signaling cascade in Plasmodium berghei

(Submitter supplied) Gametogenesis is essential for malaria parasite transmission, but the molecular mechanism of this process remains to be refined. Here, we identified a G-protein-coupled receptor 180 (GPR180) that plays a critical role in signal transduction during gametogenesis in Plasmodium. P. berghei GPR180 was predominantly expressed in gametocytes and ookinetes and associated with the plasma membrane in female gametes and ookinetes. more...
Organism:
Plasmodium berghei
Type:
Expression profiling by high throughput sequencing
Platform:
GPL29857
4 Samples
Download data: TXT
Series
Accession:
GSE198287
ID:
200198287

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