GEO DataSets

(Submitter supplied) The transcriptional activities of c-Myb and its oncogenic variant v-Myb were compared by expressing them in primary human monocytes using recombinant adenovirus vectors. All the samples were compared to cells infected with a control adenovirus expressing only GFP. The results showed that v-Myb, which differs from c-Myb only by N- and C-terminal deletions and eleven amino acid substitutions, has a qualitatively different transcriptional activity. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS1427

Platform:

GPL570

6 Samples

Download data: CEL

Analysis of monocytes infected with adenovirus expressing c-Myb or its oncogenic variant v-Myb, a mutated (11 AA substitutions) and truncated (N- and C-termini) version of c-Myb. Results identify dramatic, qualitative changes in the transcriptional acitivity of c-Myb caused by oncogenic mutations.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 infection sets

Platform:

GPL570

Series:

GSE2816

6 Samples

Download data: CEL