GEO DataSets

Effect of 1mM 4-phenylbutyrate (PBA) at 0, 12 and 24 hours in cystic fibrosis bronchial epithelial model cell line IB3-1. PBA modulates heat shock protein and promotes trafficking of deltaF508 cystic fibrosis transmembrane conductance regulator (CFTR).

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 time sets

Platform:

GPL97

Series:

GSE620

11 Samples

Download data: CEL

Analysis of peripheral blood B cells isolated from 41 untreated chronic lymphocytic leukemia (CLL) patients and 11 age-matched control subjects. B-cell CLL is the most common type of leukemia, mainly affecting adults. Results provide insight into molecular mechanisms underlying CLL pathogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL97

Series:

GSE22529

52 Samples

Download data: CEL

Temporal analysis of PBMCs collected from 25 German relapsing-remitting multiple sclerosis patients treated with recombinant interferon-beta-1b (rIFN-β-1b, 250 µg every other day) for 2 years. Results provide insight into molecular mechanisms of IFN-b action.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 gender, 5 time sets

Platform:

GPL97

Series:

GSE24427

125 Samples

Download data: CEL

Analysis of PBMCs from children (2-18 years) with newly diagnosed type 1 or 2 diabetes (T1D or T2D). One and 4 month samples were obtained from 20 of the T1D patients. Results provide insight into molecular mechanisms that distinguish T1D and T2D and those that are common to both forms of diabetes.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 disease state, 2 gender, 4 time sets

Platform:

GPL97

Series:

GSE9006

117 Samples

Download data: CEL

Analysis of HITC6 vascular smooth muscle cells (SMC) before and after serum withdrawal-induced formation of cords showing end-to-end and side-to-side SMC assemblies that approximate the association of SMCs in the arterial media. Results provide insight into molecular basis of SMC cord morphogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 time sets

Platform:

GPL97

Series:

GSE21363

6 Samples

Download data: CEL, CHP

Analysis of umbilical vein endothelial cells (HUVEC) treated with VEGF-A for up to 6 hours in vitro. VEGF-A is a major trigger of vasculogenesis and physiologic angiogenesis. Results provide insight into the molecular mechanisms underlying the vasculogenic and angiogenic activity of VEGF-A.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent, 5 time sets

Platform:

GPL97

Series:

GSE10778

5 Samples

Download data: CEL, CHP

Analysis of peripheral blood mononuclear cells from shoe factory workers exposed to benzene. Benzene is a leukemogen. Results provide insight into molecular mechanisms of benzene carcinogenicity.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 agent sets

Platform:

GPL97

Series:

GSE9569

16 Samples

Download data: CEL

Analysis of cultured peripheral blood mononuclear cells (PBMCs) stimulated with interleukin-12 (IL-12). PBMCs obtained from 7 donors. IL-12 plays a central role in adaptive and innate immunity. Results provide further insight into the effects of IL-12 on the immune response.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent, 7 individual sets

Platform:

GPL97

Series:

GSE12839

14 Samples

Download data: CEL

Analysis of skeletal muscles from patients with limb girdle muscular dystrophy 2A (LGMD2A). LGMD2A is a recessive genetic disorder caused by mutations in calpain 3 (CAPN3). Results provide insight into the molecular pathogenesis of LGMD2A.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL97

Series:

GSE11681

17 Samples

Download data: CEL

Comparison of UCB1 and UCB2 cells, two distinct isogenic mesenchymal stem/stromal cell (MSC) populations isolated from umbilical cord blood. UCB1 and UCB2 display phenotypic differences. Results provide insight into the molecular basis of the phenotypic heterogeneity among MSC populations.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 specimen sets

Platform:

GPL97

Series:

GSE6029

9 Samples

Download data: CEL

Analysis of mononuclear cells from bone marrow or peripheral blood from a training set of 163 adult patients with cytogenetically normal acute myeloid leukemia (CN-AML). Patients with CN-AML show heterogeneous treatment outcomes. Results provide insight into a prognostic gene signature for CN-AML.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 tissue sets

Platform:

GPL97

Series:

GSE12417

163 Samples

Download data: CEL

Analysis of medial and lateral substantia nigras (SNs) from post-mortem brain samples obtained from individuals with sporadic Parkinson's disease (PD). The SN exhibits extensive tissue damage in PD. Results provide insight into the pathogenesis of PD.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 23 individual, 3 tissue sets

Platform:

GPL97

Series:

GSE8397

47 Samples

Download data: CEL

Analysis of patient matched normal and stage 1 or stage 2 clear cell renal cell carcinoma (cRCC) tumors. Results provide insight into the molecular pathogenesis of cRCC.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 disease state, 10 individual sets

Platform:

GPL97

Series:

GSE6344

20 Samples

Download data: CEL

Analysis of muscle biopsy specimens from patients with various muscle diseases. Results provide insight into the diagnosis and pathogenesis of muscle diseases.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 11 disease state sets

Platform:

GPL97

Series:

GSE3307

119 Samples

Download data: CEL

Analysis of SVGR2 glial cells resistant to the human polyomavirus JCV, the causative agent of progressive multifocal leukoencephalopathy. SVGR2 cells are derived from susceptible glial cells (SVG-A). Results provide insight into the molecular mechanisms underlying susceptibility to JCV infection.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 cell type sets

Platform:

GPL97

Series:

GSE7819

6 Samples

Download data: CEL, CHP, EXP

Analysis of breast cancer MCF-7 cells following the induction of expression of nuclear LIM-only protein 4 (LMO4). LMO4 is upregulated in breast cancer. Results provide insight into the role of LMO4 in promoting tumor formation.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL97

Series:

GSE7382

6 Samples

Download data: CEL

Analysis of MCF-7 breast cancer cells treated with 100 nM dioxin. Although dioxin is causative for many types of cancers, low exposure to dioxin is associated with a decreased incidence of breast carcinoma. Results provide insight into the molecular basis of this protective effect.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL97

Series:

GSE7765

6 Samples

Download data: CEL, CHP, EXP

Analysis of circulating blood reticulocytes from umbilical cords and normal adults. Reticulocytes are immature red blood cells containing residual RNA. Results provide insight into the molecular basis of terminal erythroid differentiation.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 development stage sets

Platform:

GPL97

Series:

GSE6236

28 Samples

Download data: CEL, EXP

Analysis of breast cancer cells that have high tumorigenic capacity. These cells express CD44 and low or undetectable levels of CD24. Results used to define a gene expression signature associated with metastasis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 disease state sets

Platform:

GPL97

Series:

GSE6883

12 Samples

Download data: CEL

Analysis of the basal plate of the placenta from midgestation to term. The basal plate is the region where maternal and fetal cells coexist. Its proper formation is required for pregnancy. Results provide insight into the molecular basis of the unique cell-cell interactions in the basal plate.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 12 age, 2 development stage sets

Platform:

GPL97

Series:

GSE5999

36 Samples

Download data: CEL