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Links from GEO DataSets

Items: 3

1.
Full record GDS4976

Spleen tyrosine kinase inhibitor effect on diffuse large B-cell lymphoma cell lines: time course

Analysis of the DHL4 and DHL6 diffuse large B-cell lymphoma (DLBCL) cell lines following treatment with R406, a spleen tyrosine kinase (SYK) inhibitor. SYK is a key component of BCR signaling which is a critical pathway in DLBCL. Results provide insight into the role of SYK in DLBCL pathogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 2 cell line, 5 time sets
Platform:
GPL3921
Series:
GSE34176
29 Samples
Download data: CEL
2.
Full record GDS4305

Glycogen synthase kinase 3 α knockdown in acute myeloid leukemia cell lines

Analysis of AML cell lines infected with shRNAs against glycogen synthase kinase 3 α and β isoforms (GSK-3α, GSK-3β). GSK-3 is a multifunctional serine threonine kinase; specific loss of GSK-3α induces differentiation in AML. Results provide insight into the role of GSK-3α in AML.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 cell line, 3 genotype/variation, 5 other sets
Platform:
GPL3921
Series:
GSE35200
44 Samples
Download data: CEL
3.
Full record GDS4269

Transforming growth factor-beta effect on Hepatocellular carcinoma Huh-7 cell line

Analysis of Hepatocellular carcinoma (HCC) Huh-7 cells stimulated with transforming growth factor-beta (TGF-β). HCC cell line Huh-7 has intact WNT pathway components. Results provide insight into the role of TGF-β in regulating WNT pathway activity in HCC cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL3921
Series:
GSE10393
4 Samples
Download data: CEL
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