GEO DataSets

Analysis of MCF-7 breast cancer cells depleted for RNF31. RNF31 is an atypical E3 ubiquitin ligase. MCF-7 is an estrogen receptor (ER) alpha positive cell line. Results provide insight into the role of RNF31 in the ER-alpha stimulated proliferation of breast cancer cells.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 protocol sets

Platform:

GPL6480

Series:

GSE46010

7 Samples

Download data: TXT

Analysis of U251 astrocyte cells infected with the influenza H5N1 virus for up to 24 hours. Results provide insight into the immune response of astrocytes to H5N1 infection.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 infection, 3 time sets

Platform:

GPL6480

Series:

GSE66597

18 Samples

Download data: TXT

Analysis of primary T lymphoblasts and derived exosomes after activation with PMA plus ionomycin. Exosomes contain specific RNA species and can be functionally transferred to recipient cells. Results provide insight into molecular mechanisms underlying the selective sorting of RNA into exosomes.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 cell type, 2 protocol sets

Platform:

GPL6480

Series:

GSE50971

8 Samples

Download data: TXT

Analysis of BEAS-2B lung epithelial cells treated with 2.5 uM arsenic trioxide for 6 months. Chronic arsenic exposure increases lung cancer risk. Results provide insight into the molecular mechanisms underlying lung carcinogenesis associated with arsenic exposure.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 agent sets

Platform:

GPL6480

Series:

GSE33520

7 Samples

Download data: TXT

Analysis of adenocarcinoma derived-SW620 colon cancer cells treated with supercritical rosemary extract (RE-2) at doses of 30, 60 and 100 μg/mL. RE contains carnosic acid and carnosol (diterpenes) and essential oils. Results provide insight into the molecular basis of RE's anticancer effects.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 4 dose sets

Platform:

GPL6480

Series:

GSE56496

8 Samples

Download data: TXT

Analysis of fetal CD34+ HSPCs expressing N-terminal truncated GATA1-mutant (GATA1s) during myeloid differentiation for 4 and 14 days. GATA1s mutations are associated with transient leukemia (TL)- in Down syndrome neonates. Results provide insight into the role of GATA1s in TL pathogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 protocol, 3 time sets

Platform:

GPL6480

Series:

GSE56332

9 Samples

Download data: TXT

Analysis of placental multinucleated giant cells (MGCs) obtained from at-term placental CD14+ macrophages cultured in DMEM-F12 containing 10% FCS and antibiotics for 9 days. Results provide insight into molecular mechanisms underlying the maturation of macrophages into MGCs.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 cell type sets

Platform:

GPL6480

Series:

GSE38747

12 Samples

Download data: TXT

Analyis of epi 4 gingival cells treated with capsaicin, the pungent compound present in red chilies. Capsaicin is an activator of transient receptor potential cation channel subfamily V member 1 (TRPV1). Results provide insight into the function of TRPV1 in gingival cells.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL6480

Series:

GSE57759

8 Samples

Download data: TXT

Analysis of IMR-90 cells cultured on plastic and treated with IL-4, IL-13 or TNFα. Type 2 inflammatory processes mediated by IL-4 and IL-13 are implicated in pathologic lung fibrogenesis. Results provide insight into molecular mechanisms underlying the onset and maintenance of pulmonary fibrosis.

Organism:

Homo sapiens

Type:

Expression profiling by array, log2 ratio, 4 agent sets

Platform:

GPL6480

Series:

GSE47542

12 Samples

Download data: TXT

Analysis of IMR-90 cells cultured on Matrigel and treated with IL-4, IL-13 or TNFα. Type 2 inflammatory processes mediated by IL-4 and IL-13 are implicated in pathologic lung fibrogenesis. Results provide insight into molecular mechanisms underlying the onset and maintenance of pulmonary fibrosis.

Organism:

Homo sapiens

Type:

Expression profiling by array, log2 ratio, 4 agent sets

Platform:

GPL6480

Series:

GSE47542

12 Samples

Download data: TXT

Analysis of MIA PaCa-2 pancreatic cancer cells overexpressing miR-193b. Aberrant expression of microRNAs occurs in various cancers, including pancreatic cancer. Results identify target genes of miR-193b.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL6480

Series:

GSE25215

4 Samples

Download data: TXT

Analysis of A549 cells treated with SiO2 NPs (diameters of 9nm and 18nm) and examined after 3hr and 22hr recovery times. Coated nanomaterials (e.g., SiO2 NPs) agglomerate less and are, thus, more easily inhalable. Results provide molecular insight into molecular basis of nanotoxicological effects.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 agent, 2 time sets

Platform:

GPL6480

Series:

GSE53700

18 Samples

Download data: TXT

Analysis of primary neonatal foreskin keratinocytes overexpressing Kruppel-like factor 9 (KLF9) for up to 7 days. KLF9 is a transcription factor that binds to GC box elements. Results identify downstream targets of KLF9.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 protocol, 3 time sets

Platform:

GPL6480

Series:

GSE36014

6 Samples

Download data: TXT

Analysis of epidermal samples from 20 individuals obtained at 9:30 am, 2:30 pm and 7:30 pm. Results identify transcripts that exhibit time-dependent expression in the epidermis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 20 individual, 3 time sets

Platform:

GPL6480

Series:

GSE35635

57 Samples

Download data: TXT

Analysis of bronchial epithelial cells from patients with severe asthma. Results provide insight into the molecular mechanisms underlying the development of severe asthma.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 disease state, 2 gender sets

Platform:

GPL6480

Series:

GSE43696

108 Samples

Download data: TXT

Analysis of placenta retrieved at delivery from healthy women who consumed up to 930mg choline/day throughout their third trimester of pregnancy. Results provide insight into the molecular mechanisms underlying the benefits of maternal choline supplementation on placental function.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 dose, 2 gender, 2 other sets

Platform:

GPL6480

Series:

GSE39290

12 Samples

Download data: TXT

Analysis of keratinocytes treated with Interleukin 17C (IL-17C) for 3 and 24 hours. IL-17C is induced in epithelia by bacterial challenge and inflammatory stimuli and upregulated in psoriatic skin lesions. Results provide insight into the role of IL-17C in the innate epithelial immune response.

Organism:

Homo sapiens

Type:

Expression profiling by array, log2 ratio, 2 agent, 2 time sets

Platform:

GPL6480

Series:

GSE32620

16 Samples

Download data: TXT

Analysis of airway smooth muscle (ASM) cells treated with glucocorticoid (GC) dexamethasone for 4 or 24h. GCs are used to treat asthma, exerting their therapeutic effects in part through modulating ASM structure/function. Results provide insight into molecular mechanisms underlying GC action in ASM.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 agent, 3 time sets

Platform:

GPL6480

Series:

GSE34313

10 Samples

Download data: TXT

Analysis of colon biopsies from inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) subjects. Colon biopsies also examined from 12 of these subjects (6 IBD, 6 IBS) after a 7-day diet high in red meat (300g/day). Results provide insight into molecular basis of IBD pathophysiology.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 2 gender, 32 individual, 2 protocol sets

Platform:

GPL6480

Series:

GSE25220

44 Samples

Download data: GPR

Analysis of HaCaT keratinocytes treated with alkylphospholipids (APLs) Ino-C2-PAF, Glc-PAF, and edelfosine. APLs interfere with a variety of key enzymes implicated in cell growth, motility, invasion, and apoptosis. Results provide insight into mechanism of action of APLs.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 agent sets

Platform:

GPL6480

Series:

GSE20722

12 Samples

Download data: TXT