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Links from GEO DataSets

Items: 17

1.

Epithelial cells in contact with bacterial supernatant

(Submitter supplied) Epithelial cells were in contact with bacteria supernatant during different times of incubation. time course supernatant 10 % MM39 Keywords: time-course
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1417
5 Samples
Download data
Series
Accession:
GSE1704
ID:
200001704
2.

interaction with bacteria or bacterial supernatant

(Submitter supplied) Epithelial cells were in contact either with live bacteria (S. aureus) or with bacterial supernatant during 3 hours. Three dependant experiment for each condition were performed. RNA from epithelial cells were extracted. Each condition was hybridized on 6 slides (3 slides with their corresponding swap) Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1521
12 Samples
Download data
Series
Accession:
GSE1853
ID:
200001853
3.

PBECs stimulated with pro-inflammatory cytokines and P. aeruginosa

(Submitter supplied) Comparison of libraries derived from primary human bronchial epithelial cells which are [i] unstimulated, [ii] stimulated with the pro-inflammatory cytokines IL1beta and TNFalpha and [iii] stimulated with heat-inactivated Pseudomonas aeruginosa (strain PAO1). Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by SAGE
Platform:
GPL4
3 Samples
Download data
Series
Accession:
GSE2056
ID:
200002056
4.

Gene expression profiling of mammary epithelial cells and their role in the predisposition to Staphylococcus aureus infections

(Submitter supplied) Background: Staphylococcus aureus is a major pathogen of humans and animals. Host genetics influence the susceptibility to S. aureus infections, and genes determining infection outcome remain to be identified. Here, we used outbred animals from a divergent selection on susceptibility towards Staphylococcus infection to explore host immunogenetics. Methodology/Principal Findings: We investigated in vitro how mammary epithelial cells (MEC) respond to live S. more...
Organism:
Ovis aries
Type:
Expression profiling by array
Platform:
GPL10427
118 Samples
Download data: TXT
Series
Accession:
GSE30390
ID:
200030390
5.

Global expression profiling of airway epithelial cells infected with Pseudomonas aeruginosa and the rsmA mutant

(Submitter supplied) Global expression profiling of airway epithelial cells infected with Pseudomonas aeruginosa and the rsmA mutant. Recent work in our laboratory investigated the impact of RsmA on a number of airway epithelial cell phenotypes including actin depolymerization, cytotoxicity and invasion. These cellular phenotypes were influenced by the positive effect of RsmA on the expression of the TTSS in P. aeruginosa (Mulcahy et al. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2287
Platform:
GPL96
6 Samples
Download data: CEL, EXP
Series
Accession:
GSE4485
ID:
200004485
6.
Full record GDS2287

Airway epithelial cell response to Pseudomonas aeruginosa rsmA mutant infection

Analysis of airway epithelial cells infected with Pseudomonas aeruginosa PAO1 or the rsmA mutant. RsmA is a small RNA-binding protein that plays a role in the regulation of virulence-related genes in P. aeruginosa. Results provide insight into the influence of RsmA-regulated functions on the host.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 genotype/variation, 2 infection sets
Platform:
GPL96
Series:
GSE4485
6 Samples
Download data: CEL, EXP
7.

Allergen induced gene expression of airway epithelial cells shows a possible role for TNF-α

(Submitter supplied) Response to allergen was studied in bronchial epithelial cell line H292. Cells were cultured and subsequently exposed to House dust mite or vessel (saline) Microarray data was analysed using bioinformatics and biostastics. We find a strong response to allergen in epithelial cells Keywords: cellular response to allergen
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3003
Platform:
GPL570
6 Samples
Download data: CEL, EXP
Series
Accession:
GSE9151
ID:
200009151
8.
Full record GDS3003

House dust mite extract effect on a bronchial epithelial cell line

Analysis of H292 bronchial epithelial cells exposed to house dust mite (HDM) extract. More than just a physical barrier, epithelium can produce mediators in response to pathogens and allergens. Results provide insight into the nature of the response of bronchial epithelial cells to HDM allergen.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL570
Series:
GSE9151
6 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS3003
ID:
3003
9.

Analysis of the in vitro transcriptional response of human pharyngeal epithelial cells to adherent pneumococci

(Submitter supplied) Infection of the human host by Streptococcus pneumoniae begins with colonization of the nasopharynx, which is mediated by adherence of bacteria to respiratory epithelium. Several studies have indicated an important role for the pneumococcal capsule in this process. Here, we used microarrays to characterize the in vitro transcriptional response of human nasopharyngeal epithelial Detroit 562 cells to adherence of serotype 2-encapsulated strain D39, serotype 19F-encapsulated strain G54, serotype 4-encapsulated strain TIGR4, and their nonencapsulated derivatives (Δcps). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3041
Platform:
GPL570
32 Samples
Download data: CEL, EXP
Series
Accession:
GSE8527
ID:
200008527
10.
Full record GDS3041

Encapsulated Streptococcus pneumoniae strains effect on pharyngeal epithelial cell line

Analysis of pharyngeal epithelial cells exposed to various encapsulated strains of Streptococcus pneumoniae. Nasopharynx colonization by S. pneumoniae is mediated by adherence to the respiratory epithelium. Results provide insight into the capsule-dependent host response to pneumococcal adherence.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 5 agent, 3 cell type, 3 dose, 2 infection sets
Platform:
GPL570
Series:
GSE8527
32 Samples
Download data: CEL, EXP
11.

Gene expression of innate immune response in endothelial cells

(Submitter supplied) Gene expression in human umbilical vein endothelial cells (HUVEC) was investigated by microarray analysis after 4 h infection with S. aureus isolated from healthy nasal carriers (n=5) and from blood (n=5) of septic patients. All bacterial isolates were spa-typed and characterized with a DNA microarray to determine the presence of virulence genes. Keywords: infection studies, pathogen, S. aureus
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4030
Platform:
GPL570
12 Samples
Download data: CEL
Series
Accession:
GSE13736
ID:
200013736
12.
Full record GDS4030

HUVECs infected with Staphylococcus aureus isolates from blood and anterior nares

Analysis of human umbilical vein endothelial cells (HUVECs) infected with S. aureus from nares of healthy carriers or from blood of septic patients (i.e. representing a disseminated disease). Results provide insight into interactions between HUVECs and virulent/non-virulent S. aureus isolates.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 infection sets
Platform:
GPL570
Series:
GSE13736
12 Samples
Download data: CEL
DataSet
Accession:
GDS4030
ID:
4030
13.

Expression data from non-infected and Salmonella Choleraesuis infected mesenteric lymph nodes

(Submitter supplied) To understand the host transcriptional response to S. enterica serovar Choleraesuis (S. Choleraesuis), the first generation Affymetrix porcine GeneChip® was used to identify differentially expressed genes in the mesenteric lymph nodes responding to infection at acute (8 hours (h), 24h, 48h post-inoculation (pi)) and chronic stages (21 days (d) pi) The objectives of this study were to identify and examine the stereotypical gene expression response within the host mesenteric lymph nodes to S. more...
Organism:
Sus scrofa
Type:
Expression profiling by array
Platform:
GPL3533
15 Samples
Download data: CEL, EXP
Series
Accession:
GSE7314
ID:
200007314
14.

Global transcriptional profiling of Staphylococcus aureus treated with berberine chloride

(Submitter supplied) Staphylococcus aureus (S. aureus) is an important human and animal pathogen, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. Berberine chloride (BBR), a natural plant product, has potent antimicrobial activity against S. aureus. We employed Affymetrix Staphylococcus aureus GeneChipsTM arrays to investigate the global transcriptional profiling of Staphylococcus aureus ATCC25923 treated with berberine chloride. more...
Organism:
Staphylococcus aureus
Type:
Expression profiling by array
Dataset:
GDS2814
Platform:
GPL1339
6 Samples
Download data: CEL
Series
Accession:
GSE7944
ID:
200007944
15.
Full record GDS2814

Berberine chloride effect on Staphylococcus aureus

Analysis of Staphylococcus aureus ATCC25923 cultures treated with berberine chloride. Results provide insight into the antimicrobial activity of berberine chloride against Staphylococcus aureus.
Organism:
Staphylococcus aureus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL1339
Series:
GSE7944
6 Samples
Download data: CEL
DataSet
Accession:
GDS2814
ID:
2814
16.

Microarray Analysis of Toxicogenomic Effects of Triclosan on Staphylococcus aureus

(Submitter supplied) In the present study, we employed Affymetrix Staphylococcus aureus GeneChip arrays to investigate the dynamics of global gene expression profiles during the cellular response of Staphylococcus aureus to triclosan, which involved initial growth inhibition and metabolism. Keywords: Transcriptome study; antimicrobial response; time course
Organism:
Staphylococcus aureus
Type:
Expression profiling by array
Dataset:
GDS2983
Platform:
GPL1339
15 Samples
Download data: CEL
Series
Accession:
GSE8861
ID:
200008861
17.
Full record GDS2983

Triclosan effect on Staphylococcus aureus: time course

Analysis of Staphylococcus aureus cultures treated for 10 or 60 minutes with 0.05 uM triclosan. At this concentration, the antimicrobial agent caused growth inhibition for about 10 min. Results provide insight into the initial molecular response of Staphylococcus aureus to triclosan.
Organism:
Staphylococcus aureus
Type:
Expression profiling by array, count, 2 agent, 3 time sets
Platform:
GPL1339
Series:
GSE8861
15 Samples
Download data: CEL
DataSet
Accession:
GDS2983
ID:
2983
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