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Links from GEO DataSets

Items: 20

1.

Glycan effect on Saccharolytic Human Distal Gut Symbiont, B. thetaiotaomicron

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Bacteroides thetaiotaomicron; Lachnospira eligens; Phocaeicola vulgatus; Bifidobacterium longum; Parabacteroides distasonis; Methanobrevibacter smithii; Agathobacter rectalis
Type:
Expression profiling by array
Platforms:
GPL1821 GPL7006
48 Samples
Download data: CEL
Series
Accession:
GSE11980
ID:
200011980
2.

Growth of B. thetaiotaomicron on purified host mucosal glycans and glycan fragments

(Submitter supplied) Bacteroides thetaiotaomicron was grown and transcriptionally profiled on a number of different host mucosal glycans and their component mono- and disaccharides.
Organism:
Bacteroides thetaiotaomicron; Lachnospira eligens; Phocaeicola vulgatus; Methanobrevibacter smithii; Parabacteroides distasonis; Agathobacter rectalis
Type:
Expression profiling by array
Platform:
GPL7006
18 Samples
Download data: CEL
Series
Accession:
GSE11962
ID:
200011962
3.

Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont: ECF mutant

(Submitter supplied) Growth of isogenic parent ('tdk strain'), 5xECF-sigma factor mutant and complemented mutant strain in the cecum of NMRI inbred mice fed a glycan-restricted, 'simple sugar' diet (35% each glucose and sucrose). Bacteria were collected from mouse distal gut 10 days after colonization.
Organism:
Bacteroides thetaiotaomicron; Bifidobacterium longum
Type:
Expression profiling by array
Platform:
GPL1821
9 Samples
Download data: CEL
Series
Accession:
GSE11953
ID:
200011953
4.

Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont

(Submitter supplied) Gene expression profiles of Bacteroides thetaiotaomicron in vitro during growth on host mucosal polysaccharides as sole carbon sources. All substrates in this series are derived from porcine gastric mucin and include mucin O-glycans and glycosaminoglycans.
Organism:
Bacteroides thetaiotaomicron; Bifidobacterium longum
Type:
Expression profiling by array
Platform:
GPL1821
21 Samples
Download data: CEL
Series
Accession:
GSE11944
ID:
200011944
5.

Transcription analysis of wild-type and chuR Bacteroides thetaiotaomicron genes in the mouse cecum

(Submitter supplied) The large-scale application of genomic and metagenomic sequencing technologies has yielded a number of insights about the metabolic potential of symbiotic human gut microbes. Bacteria that colonize the mucosal layer that overlies the gut epithelium have access to highly-sulfated polysaccharides (i.e., mucin oligosaccharides and glycosaminoglycans), which they could potentially forage as nutrient sources. more...
Organism:
Lactobacillus delbrueckii; Bacteroides thetaiotaomicron; Streptococcus thermophilus; Lacticaseibacillus casei; Bifidobacterium animalis; Agathobacter rectalis; Bifidobacterium longum
Type:
Expression profiling by array
Platform:
GPL11169
12 Samples
Download data: CEL
Series
Accession:
GSE25415
ID:
200025415
6.

Coordinate regulation of glycan degradation and polysaccharide capsule biosynthesis by a prominent human gut symbiont

(Submitter supplied) Analysis of B. thetaiotaomicron trans-envelope signaling mutants in ECF-sigma factors, anti-sigma factors and SusC-like transporters.
Organism:
Bacteroides thetaiotaomicron; Bacteroides thetaiotaomicron VPI-5482; Bifidobacterium longum
Type:
Expression profiling by array
Platform:
GPL1821
22 Samples
Download data: CEL
Series
Accession:
GSE14592
ID:
200014592
7.

Cis-encoded sRNAs repress expression of polysaccharide utilization loci in Bacteroides fragilis 638R

(Submitter supplied) The phylum Bacteroidetes is a major component of the human gut microbiota which has a broad impact on the development and physiology of its host, and a potential role in a wide range of disease syndromes. The predominance of Bacteroidetes and the genus Bacteroides in the distal gut is due in large part to the expansion of paralogous gene clusters, termed Polysaccharide Utilization Loci (PULs), dedicated to the uptake and catabolism of host derived and dietary polysaccharides. more...
Organism:
Bacteroides fragilis 638R
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21110
2 Samples
Download data: WIG
Series
Accession:
GSE74807
ID:
200074807
8.

Cis-encoded sRNAs repress expression of polysaccharide utilization loci in Bacteroides fragilis 638R

(Submitter supplied) The phylum Bacteroidetes is a major component of the human gut microbiota which has a broad impact on the development and physiology of its host, and a potential role in a wide range of disease syndromes1-3. The predominance of Bacteroidetes and the genus Bacteroides in the distal gut is due in large part to the expansion of paralogous gene clusters, termed Polysaccharide Utilization Loci (PULs), dedicated to the uptake and catabolism of host derived and dietary polysaccharides4,5. more...
Organism:
Bacteroides fragilis 638R
Type:
Expression profiling by array; Third-party reanalysis
Platform:
GPL15788
4 Samples
Download data: CALLS, PAIR, TXT
Series
Accession:
GSE73107
ID:
200073107
9.

Effects of Diet on Resource Utilization by a Model Human Gut Microbiota Containing Bacteroides cellulosilyticus WH2, a Symbiont with an Extensive Glycobiome (RNA-Seq)

(Submitter supplied) The human gut microbiota is an important metabolic organ, yet little is known about how its individual species interact, establish dominant positions, and respond to changes in environmental factors such as diet. In this study, gnotobiotic mice were colonized with an artificial microbiota comprising 12 sequenced human gut bacterial species and fed oscillating diets of disparate composition. Rapid, reproducible, and reversible changes in the structure of this assemblage were observed. more...
Organism:
Bacteria; Bacteroides cellulosilyticus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL17330 GPL17468
116 Samples
Download data: TXT
Series
Accession:
GSE48993
ID:
200048993
10.

Effects of Diet on Resource Utilization by a Model Human Gut Microbiota Containing Bacteroides cellulosilyticus WH2, a Symbiont with an Extensive Glycobiome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Dorea longicatena DSM 13814; [Clostridium] scindens ATCC 35704; Faecalibacterium prausnitzii M21/2; Collinsella aerofaciens ATCC 25986; Thomasclavelia spiroformis DSM 1552; Bacteroides cellulosilyticus; Bacteroides sp. WH2; Bacteria; Bacteroides ovatus ATCC 8483; Bacteroides uniformis ATCC 8492; Phocaeicola vulgatus ATCC 8482; Parabacteroides distasonis ATCC 8503; Bacteroides thetaiotaomicron VPI-5482; Blautia obeum ATCC 29174; [Ruminococcus] torques ATCC 27756; Bacteroides caccae ATCC 43185; Agathobacter rectalis ATCC 33656
Type:
Expression profiling by high throughput sequencing; Other; Expression profiling by array
5 related Platforms
895 Samples
Download data: CEL, CHP, TXT
Series
Accession:
GSE48537
ID:
200048537
11.

Effects of Diet on Resource Utilization by a Model Human Gut Microbiota Containing Bacteroides cellulosilyticus WH2, a Symbiont with an Extensive Glycobiome (GeneChip)

(Submitter supplied) The human gut microbiota is an important metabolic organ, yet little is known about how its individual species interact, establish dominant positions, and respond to changes in environmental factors such as diet. In this study, gnotobiotic mice were colonized with an artificial microbiota comprising 12 sequenced human gut bacterial species and fed oscillating diets of disparate composition. Rapid, reproducible, and reversible changes in the structure of this assemblage were observed. more...
Organism:
Bacteroides sp. WH2; Bacteroides uniformis ATCC 8492; Phocaeicola vulgatus ATCC 8482; Parabacteroides distasonis ATCC 8503; Blautia obeum ATCC 29174; [Clostridium] scindens ATCC 35704; Bacteroides thetaiotaomicron VPI-5482; [Ruminococcus] torques ATCC 27756; Bacteroides caccae ATCC 43185; Thomasclavelia spiroformis DSM 1552; Agathobacter rectalis ATCC 33656; Dorea longicatena DSM 13814; Bacteroides ovatus ATCC 8483; Faecalibacterium prausnitzii M21/2; Collinsella aerofaciens ATCC 25986
Type:
Expression profiling by array
Platform:
GPL9803
168 Samples
Download data: CEL, CHP
Series
Accession:
GSE48532
ID:
200048532
12.

Effects of Diet on Resource Utilization by a Model Human Gut Microbiota Containing Bacteroides cellulosilyticus WH2, a Symbiont with an Extensive Glycobiome (COPRO-Seq)

(Submitter supplied) The human gut microbiota is an important metabolic organ, yet little is known about how its individual species interact, establish dominant positions, and respond to changes in environmental factors such as diet. In this study, gnotobiotic mice were colonized with an artificial microbiota comprising 12 sequenced human gut bacterial species and fed oscillating diets of disparate composition. Rapid, reproducible, and reversible changes in the structure of this assemblage were observed. more...
Organism:
Bacteria
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL17330 GPL17329 GPL11535
611 Samples
Download data: TXT
Series
Accession:
GSE48193
ID:
200048193
13.

In vitro and in vivo transcriptional profiling of Bacteroides thetaiotaomicron

(Submitter supplied) Transcriptional profiling of Bacteroides thetaiotaomicron was performed on samples taken from (i) chemostat cultures (in vitro) and (ii) from the ceca of gnotobiotic monoassociated NMRI mice (in vivo). In vitro profiles were obtained from biological duplicate cultures taken at five timepoints from log to stationary phase in three types of media: (i) minimal media glucose (MM-G), (ii) minimal media maltotriose (MM-M), and (iii) rich media (TYG). more...
Organism:
Bacteroides thetaiotaomicron; Bifidobacterium longum
Type:
Expression profiling by array
Dataset:
GDS1849
Platform:
GPL1821
42 Samples
Download data
Series
Accession:
GSE2231
ID:
200002231
14.
Full record GDS1849

Intestine-adapted bacterial symbiont response to polysaccharide and simple sugar diets

Analysis of Bacteroides thetaiotaomicron (BT) from the ceca of mice on polysaccharide or simple sugar diets. BT is involved in the breakdown of plant polysaccharides. BT-colonized mice is a human gut ecosystem model. Results identify genes that may endow flexibility in adapting to dietary changes.
Organism:
Bacteroides thetaiotaomicron; Bifidobacterium longum
Type:
Expression profiling by array, count, 5 growth protocol, 2 protocol, 16 time sets
Platform:
GPL1821
Series:
GSE2231
42 Samples
Download data
15.

Gnotobiotic mouse cecal epithelium; B.thetaiotaomicron-B. longum mono- versus bi-association, PR chow, NMRI

(Submitter supplied) Laser captured cecal epithelium from gnotobiotic mice colonized with B. thetaiotaomicron or B. longum (mono-association) or B. thetaiotaomicron bi-association with B. longum. Samples were derived from 10d colonizations of NMRI mice fed a standard-chow polysaccharide rich (PR) diet. Keywords: Germ-free vs. Mono-associations or Bi-association, in vivo
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL1261 GPL1981
16 Samples
Download data
Series
Accession:
GSE5870
ID:
200005870
16.

B. thetaiotaomicron or B. longum mono-association vs. bi-association

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Bacteroides thetaiotaomicron; Bifidobacterium longum
Type:
Expression profiling by array
Platform:
GPL1821
34 Samples
Download data
Series
Accession:
GSE5869
ID:
200005869
17.

B.thetaiotaomicron mono-association versus B. thetaiotaomicron co-colonization with B. animalis or L. casei, PR chow, B6

(Submitter supplied) Genome wide transcriptional comparison of B. thetaiotaomicron mono-association vs. B. thetaiotaomicron bi-association with B.animalis or L. casei. Cecal populations from 20d colonizations with B6 gnotobiotic mice fed a standard-chow polysaccharide rich (PR) diet (n=5 samples/group) were profiled. Keywords: Mono-association vs. Bi-association, in vivo
Organism:
Bacteroides thetaiotaomicron; Bifidobacterium longum
Type:
Expression profiling by array
Platform:
GPL1821
9 Samples
Download data
Series
Accession:
GSE5867
ID:
200005867
18.

B.thetaiotaomicron mono-association versus B. thetaiotaomicron co-colonization with B. longum, PR chow, B6

(Submitter supplied) Genome wide transcriptional comparison of B. thetaiotaomicron mono-association vs. B. thetaiotaomicron bi-association with B. longum. Cecal populations from 10d colonizations with b6 gnotobiotic mice fed a standard-chow polysaccharide rich (PR) diet (n=5 samples/group) were profiled. Keywords: Mono-association vs. Bi-association, in vivo
Organism:
Bacteroides thetaiotaomicron; Bifidobacterium longum
Type:
Expression profiling by array
Platform:
GPL1821
10 Samples
Download data
Series
Accession:
GSE5866
ID:
200005866
19.

B.thetaiotaomicron or B. longum mono-association versus B. thetaiotaomicron/B. longum co-colonization, PR chow, NMRI

(Submitter supplied) Genome wide transcriptional comparison of B. thetaiotaomicron or B. longum mono-association vs. B. thetaiotaomicron bi-association with B. longum. Cecal populations from 10d colonizations with NMRI gnotobiotic mice fed a standard-chow polysaccharide rich (PR) diet (n=5 samples/group) were profiled. Keywords: Mono-association vs. Bi-association, in vivo
Organism:
Bacteroides thetaiotaomicron; Bifidobacterium longum
Type:
Expression profiling by array
Platform:
GPL1821
15 Samples
Download data
Series
Accession:
GSE5865
ID:
200005865
20.

Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats

(Submitter supplied) We used Affymetrix GeneChips to determine the physiological differences between biofilm and planktonic cells of Bacteroides thetaiotaomicron strain VPI-5482 (ATCC 29148) by comparing gene expression. For this purpose, B. thetaiotaomicron cells were grown in sterile, continuous flow bioreactors fed with tryptone, yeast extract, glucose (TYG) medium. The bioreactors were controlled at a temperature of 37C using a water jacket and a recirculating water heater. more...
Organism:
Phocaeicola vulgatus; Methanobrevibacter smithii; Bacteroides thetaiotaomicron VPI-5482; Parabacteroides distasonis; Bifidobacterium longum; Bacteroides thetaiotaomicron; Lachnospira eligens; Agathobacter rectalis
Type:
Expression profiling by array
Platforms:
GPL1821 GPL7006
12 Samples
Download data: CEL
Series
Accession:
GSE38534
ID:
200038534
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