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RARA haploinsufficiency modestly influences the phenotype of APL.
PubMed Full text in PMC Similar studies Analyze with GEO2R
Effect of PML/RARA on the transcriptome of preleukemic early promyelocytes vs PML/RARA-Flt3ITD leukemic promyelocytes
Effect of PML/RARa on the transcriptome of maturing myeloid populations in vivo
The ability of PML/RARα to initiate leukemia is associated with markedly increased proliferation of promyelocytes despite minor changes in the transcriptome and epigenome.
PubMed Full text in PMC Similar studies SRA Run Selector
Variant acute promyelocytic leukemia (APL) bone marrow aCGH
PubMed Similar studies Analyze with GEO2R
Conserved progression mutations revealed by sequencing a mouse acute promyelocytic leukemia genome
aCGH data from mouse APL tumors
Exon array data from mouse APL tumors
The induced APL cells generated by the transplantation of PML-RARA-transduced human CD34+ hematopoietic cells into immunodeficient mice
Multi-omics and machine learning reveal context-specific gene regulatory activities of PML-RARA in Acute Promyelocytic Leukemia
PubMed Full text in PMC Similar studies
Multi-omics and machine learning reveal context-specific gene regulatory activities of PML-RARA in Acute Promyelocytic Leukemia [ATAC-seq]
Effect of Protease-resistant PML-RARα on the leukemogenic potential in a mouse model of Acute Promyelocytic Leukemia
Effect of protease-resistant (PML-RAR)α on U937 cell line
PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet
Expression data from patient female with acute promyelicytic leukemia
Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia
PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector
Torque Teno Mini Virus as a cause of childhood acute promyelocytic leukemia lacking PML/RARA fusion
PubMed Similar studies Analyze with GEO2RSRA Run Selector
Identifying STRN3-RARA as a new fusion gene for acute promyelocytic leukemia [RNA-seq 2]
PubMed Similar studies
Identifying STRN3-RARA as a new fusion gene for acute promyelocytic leukemia
Identifying STRN3-RARA as a new fusion gene for acute promyelocytic leukemia [RNA-seq]
Identifying STRN3-RARA as a new fusion gene for acute promyelocytic leukemia [CUT&TAG]
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