Similar studies for GEO DataSets (Select 200029125) - GEO DataSets

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Items: 20

Select item 2000291251.

Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13272
25 Samples

Download data: BAM, BIGWIG

Series

Accession:: GSE29125

ID:: 200029125

PubMed Full text in PMC Similar studies

Select item 2000291242.

Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L (ChIP-Seq data)

(Submitter supplied) TORC1 is a structurally and functionally conserved multiprotein complex that regulates many aspects of eukaryote growth including the synthesis and assembly of ribosomes. The protein kinase activity of this complex is responsive to environmental cues and is potently inhibited by the natural product macrolide rapamycin. Insights into how TORC1 regulates growth have been provided with the recent identification of the rapamycin-sensitive phosphoproteome in yeast. more...

Organism:: Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13272
9 Samples

Download data: BAM, BIGWIG

Series

Accession:: GSE29124

ID:: 200029124

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000291223.

Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L (mRNA-Seq data)

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13272
16 Samples

Download data: BAM

Series

Accession:: GSE29122

ID:: 200029122

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000811124.

Genome-wide location analysis of Abf1 and Reb1 in Saccharomyces cerevisiae

(Submitter supplied) Abf1 and Reb1, two general regulatory factors playing roles at promoters and other genome functional sites in budding yeast, were mapped genome-wide by ChIP-sequencing using strains expressing TAP-tagged versions of the proteins. As expected on the basis of previous in silico analysis of promoter regions, we found that these factors are enriched at the promoters of ribosome biogenesis (Ribi) genes, a large regulon of more than 200 genes required for ribosome biosynthesis and assembly, and known to be coordinately regulated in response to nutrient availability and cellular growth rate.

Organism:: Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL17342
4 Samples

Download data: BED

Series

Accession:: GSE81112

ID:: 200081112

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000076605.

Sch9 Is a Major Target of TORC1 in Saccharomyces cerevisiae

(Submitter supplied) The Target Of Rapamycin (TOR) protein is a Ser/Thr kinase that functions in two distinct multiprotein complexes: TORC1 and TORC2. These conserved complexes regulate many different aspects of cell growth in response to intra- and extracellular cues. Here we report the first bona fide substrate of yeast TORC1: the AGC-kinase Sch9. Six amino acids in the c-terminus of Sch9 are directly phosphorylated by TORC1. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL884
17 Samples

Download data: TXT

Series

Accession:: GSE7660

ID:: 200007660

Select item 2001190896.

Dot6 is a major regulator of cell size and a transcriptional activator of ribosome biogenesis in the opportunistic yeast Candida albicans

(Submitter supplied) In most species, size homeostasis appears to be exerted in late G1 phase as cells commit to division, called Start in yeast and the Restriction Point in metazoans. This size threshold couples cell growth to division and thereby establishes long-term size homeostasis. Our former investigations have shown that hundreds of genes markedly altered cell size under homeostatic growth conditions in the opportunistic yeast Candida albicans, but surprisingly only few of these overlapped with size control genes in the budding yeast Saccharomyces cerevisiae. more...

Organism:: Candida albicans

Type:: Expression profiling by array

Platform:: GPL9818
3 Samples

Download data: TXT

Series

Accession:: GSE119089

ID:: 200119089

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000589927.

State Transitions in the TORC1 Signaling Pathway and Information Processing in S. cerevisiae

(Submitter supplied) TOR kinase complex I (TORC1) is a key regulator of cell growth and metabolism in all eukaryotes. Previous studies in yeast have shown that three GTPases, Gtr1, Gtr2 and Rho1, bind TORC1 in nitrogen and amino acid starvation conditions to block phosphorylation of the S6 kinase Sch9 and activate protein phosphatase 2A (PP2A). This leads to down-regulation of 450 Sch9-dependent protein and ribosome synthesis genes, and up-regulation of 100 PP2A-dependent nitrogen assimilation and amino acid synthesis genes. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL16244
16 Samples

Download data: GPR

Series

Accession:: GSE58992

ID:: 200058992

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000083798.

Stb3 deletion affects gene expression within 10 minutes of glucose addition

(Submitter supplied) Microarrays were conducted to asses the effect of Stb3 deletion in immediate transcriptional induction in response to glucose Keywords: Stb3, immediate glucose induction, growth genes.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Dataset:: GDS2804
Platform:: GPL90
8 Samples

Download data: CEL

Series

Accession:: GSE8379

ID:: 200008379

Select item 28049.

Quiescent stb3 null mutant response to glucose

Analysis of the response of quiescent stb3 null cells to glucose. STB3 encodes a protein that binds to the Ribosomal RNA Processing Element, a DNA sequence motif that regulates genes needed for growth. Results provide insight into Stb3’s role during the transition from quiescence to rapid growth.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, transformed count, 2 genotype/variation, 2 growth protocol sets

Platform:: GPL90
Series:: GSE8379
8 Samples

Download data: CEL

DataSet

Accession:: GDS2804

ID:: 2804

Select item 20020158010.

Fission Yeast TORC1 Promotes Cell Proliferation through Sfp1, a Transcription Factor Involved in Ribosome Biogenesis

(Submitter supplied) To study the TORC1-mediated transcriptional regulation of the genes involved in ribosome biosynthesis in fission yeast

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16192
4 Samples

Download data: XLSX

Series

Accession:: GSE201580

ID:: 200201580

PubMed Similar studies

Select item 20003914711.

Genome-wide Ifh1p occupancy at the OX growth phase and RC quiescent phase of the yeast metabolic cycle

(Submitter supplied) We found ribosomal transcription factor Ifh1p is dynamically acetylated and phosphorylated in response to nutrient cues. ChIP-seq data revealed dynamic binding to ribosomal genes (RP) during the OX growth phase of the yeast metabolic cycle (YMC) when RP genes are highly induced, and weaker binding in the RC quiescent-like phase. Besides RP genes, our ChIP-seq data also reveals binding of Ifh1p to non-RP genes such as translation factors and metabolic genes.

Organism:: Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13272
4 Samples

Download data: WIG

Series

Accession:: GSE39147

ID:: 200039147

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Select item 20013453412.

Genome-wide binding of Rpb1 (the largest subunit of the RNA polymerase II) to the chromatin state in bud27∆ and wild-type mutant strains (ChIP-seq)

(Submitter supplied) Comparison of the average normalised ChIP-seq signal over protein-coding genes in bud27∆ mutants strain and wild-type.

Organism:: Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13821
8 Samples

Download data: BW

Series

Accession:: GSE134534

ID:: 200134534

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20013139013.

Prefoldin-like Bud27 influences the transcription of ribosomal components and ribosome biogenesis in Saccharomyces cerevisiae

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:: GPL13821
18 Samples

Download data: BW

Series

Accession:: GSE131390

ID:: 200131390

PubMed Full text in PMC Similar studies

Select item 20013138914.

Global analyisis to study the bud27∆ and WT treated with rapamycin regarding to WT [RNA-seq]

(Submitter supplied) RNA extraction for global analyisis and sequencing, to study the bud27∆ mutant and WT treated with rapamycin regarding to WT.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13821
6 Samples

Download data: TXT

Series

Accession:: GSE131389

ID:: 200131389

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Select item 20013138815.

Genome-wide maps of Bud27 binding to the chromatin [ChIP-seq]

(Submitter supplied) The goal of this study is to analyse genome-wide the binding profile of Bud27 prefoldin-like to the genes or other genomic regions in order to know which genes could be transcriptionally regulated by this protein and to elucidate the contribution of Bud27 to the transcription. Average normalised ChIP-seq signal for Bud27 prefoldin-like binding in a S.cerevisiae wild-type strain.

Organism:: Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13821
4 Samples

Download data: BW

Series

Accession:: GSE131388

ID:: 200131388

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20014103416.

Rph1 coordinates transcription of ribosomal protein gene and ribosomal RNA to control cell growth under nutrient stress conditions

(Submitter supplied) Coordinated regulation of ribosomal RNA (rRNA) and ribosomal protein gene (RPG) transcription by eukaryotic RNA polymerases (RNAP) is a key requirement for growth control. Although evidence for balance between RNPI-mediated 35S rRNA production and RNAPII-mediated RPG transcription have been described, the molecular basis is obscure. Here, we found that Rph1 modulates the transcription status of both rRNA and RPG in yeast. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL27812
24 Samples

Download data: TXT, XLSX

Series

Accession:: GSE141034

ID:: 200141034

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20001139717.

Effects of Mediator subunit gene-deletions under conditions that repress ribosome synthesis

(Submitter supplied) Transcriptional repression of ribosomal components and tRNAs is coordinately regulated in response to a wide variety of environmental stresses. Part of this response involves the convergence of different nutritional and stress signaling pathways on Maf1, a protein that is essential for repressing transcription by RNA polymerase (pol) III in Saccharomyces cerevisiae. Here we identify the functions buffering yeast cells that are unable to down-regulate transcription by RNA pol III. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL1229
24 Samples

Download data: TXT

Series

Accession:: GSE11397

ID:: 200011397

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000194418.

Genome-wide binding of Fhl1 and Ifh1 +/- Rapamycin

(Submitter supplied) Array design -Platform: amino-silane coated glass slides (GAPS II, Corning) -S. cerevisiae intergenic regions amplified from S288C genomic DNA (ResGen) using the intergenic region primer oligonucleotides (ResGen) (Harismendy et al. EMBO J. 22(18): 4738-4747, 2003). The primers allow the amplification of the sequence located on either side of elements such as open reading frames, tRNAs, small nuclear RNAs, Ty elements, solo δ, etc. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL1695
15 Samples

Download data: TIFF

Series

Accession:: GSE1944

ID:: 200001944

Select item 20000193019.

Fhl1 and lfh1 ChIP-chip

(Submitter supplied) Fhl1-9myc ChIP-chip, YPD, OD600=0.8, 2 arrays with duplicate spotting of yeast intergenic regions. AND Ifh1-9myc ChIP-chip, cells grown in YPD, OD600=0.8, 2 arrays with duplicate spotting of yeast intergenic regions. Keywords = Fhl1 Keywords: other