Similar studies for GEO DataSets (Select 200033898) - GEO DataSets

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Items: 3

Select item 2000338981.

Locust flight muscle: hypoxia-treated vs control

(Submitter supplied) Background: Hypoxia can affect aerobic organisms profoundly. Biological responses to extreme hypoxia have been well studied. However, it is not well characterized how living organisms respond to mild hypoxia, and how they distinguish different levels of hypoxia. Results: We examined the transcriptional responses of locusts using microarrays to reveal their strategies to cope with mild hypoxia. Mitochondrial activities were systemically suppressed, mainly involving energy production and mitochondrial biogenesis. more...

Organism:: Locusta migratoria

Type:: Expression profiling by array

Platform:: GPL14920
6 Samples

Download data: GPR

Series

Accession:: GSE33898

ID:: 200033898

Select item 2000433272.

Locust flight muscle: Tibetan Plateau population vs. North China Plain population

(Submitter supplied) Background: Responses to hypoxia have been investigated in many species; however, comparative study between conspecific geographical populations in different altitude regions is rare, especially for invertebrates . The migratory locust, Locusta migratoria, is widely distributed both on high-altitude Tibetan Plateau (TP) and on low-altitude North China Plain (NP). TP locusts have inhabited Tibetan Plateau since Quaternary glaciations events and thus probably have evolved superior capacity to deal with hypoxia. more...

Organism:: Locusta migratoria

Type:: Expression profiling by array

Platform:: GPL14920
18 Samples

Download data: GPR

Series

Accession:: GSE43327

ID:: 200043327

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Select item 2001732333.

Acute, chronic, normobaric and hypobaric hypoxia elicit differential responses in the mouse retina on the genomic level

(Submitter supplied) Purpose: Bulk RNA-Seq of wild-type mice retina after different hypoxic exposures, to evaluate the influence on retinal pathologies. Methods: Retinal mRNA profiles of C57BL/6J mice after 6 different hypoxic exposures were generated by deep sequencing (n=6) using paired-end high output sequencing (Illumina Novaseq 6000). Results: Longitudinal studies over 11 weeks in normobaric hypoxia revealed four classes of genes that adapted differentially to the long-term hypoxic condition. more...