Similar studies for GEO DataSets (Select 200077811) - GEO DataSets

Select item 2000778111.

Transcriptomic Effects of SSX2 on a Prostate Cancer Cell Line

(Submitter supplied) Prostate cancer is the most commonly diagnosed malignancy in the United States. While the majority of cases are cured with radiation or surgery, about 1/3 of patients will develop metastatic disease which there is no cure, and has a life expectancy of less than 5 years. Identification of antigens associated with this transition to metastatic disease is crucial for future therapies. One such antigen of interest is the SSX gene family, which are cancer/testis antigens that are associated with the epithelial to mesenchymal transition in other cancer types. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17586
9 Samples

Download data: CEL, CHP

Series

Accession:: GSE77811

ID:: 200077811

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000622862.

Comparison of microRNA expression between prostate adenocarcinoma cells, DU-145 and immortalized normal cells, PWR-1E

(Submitter supplied) The primary goal of this experiment was to determine the endogenous miRNA that are differentially expressed between prostate adenocarcinoma cells, DU-145 and prostate immortalized epithelial cells, PWR-1E. Subsequently, we performed other analysis with BLAST and in silico algorithm searches to determine the appropriate miRNA that could regulate a novel gene MIEN1.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL19283
2 Samples

Download data: TXT

Series

Accession:: GSE62286

ID:: 200062286

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000333173.

Gene expression profiling of mouse prostate stem cells

(Submitter supplied) The mouse prostate tissue exhibits strong power of regeneration, indicating the exisistence of prostate stem cells. Previously we showed that a single mouse prostate cells defined by Lin-CD44+CD133+Sca-1+CD117+ phenotype can generate a prostate after transplantation in vivo. In this study, we compared gene expression profiles of mouse prostate stem cells ( Lin-CD44+CD133+Sca-1+CD117+) and prostate non-stem cells (Lin-CD44-CD133-Sca-1-CD117-).

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL7202
9 Samples

Download data: TXT

Series

Accession:: GSE33317

ID:: 200033317

Select item 2000333164.

The effect of androgen deprivation on human prostate xenograft tumor LuCaP35

(Submitter supplied) Androgen deprivation is a standard of care front-line therapy for human prostate cancer, however, majority of patients will eventally develop resistance to androgen deprivation. In this study, using a human prostate cancer xenograft model -LuCaP35, we examiend the gene expression changes after castration.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4120
Platform:: GPL570
10 Samples

Download data: CEL, TXT

Series

Accession:: GSE33316

ID:: 200033316

Select item 41205.

Androgen deprivation effect on prostate xenograft tumor LuCaP35

NOD/SCID mice with established LuCaP35 xenografts were castrated, and tumors were isolated 4 weeks later. Androgen deprivation regresses androgen-dependent disease, but relapse often occurs in an androgen-independent manner. Results provide insight into the molecular basis of castration resistance.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL570
Series:: GSE33316
10 Samples

Download data: CEL

DataSet

Accession:: GDS4120

ID:: 4120

Select item 2001783306.

An integrated functional and clinical genomics approach reveal genes driving aggressive metastatic prostate cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL20301 GPL24676
16 Samples

Download data: BED

Series

Accession:: GSE178330

ID:: 200178330

PubMed Full text in PMC Similar studies

Select item 2001783297.

An integrated functional and clinical genomics approach reveal genes driving aggressive metastatic prostate cancer [ATAC-Seq]

(Submitter supplied) Genomic sequencing of many thousands of tumors has revealed many genes associated with specific types of cancer. Similarly, large scale CRISPR functional genomics efforts have mapped genes required for proliferation or survival in hundreds of cancer cell lines. Despite this, for specific disease subtypes, such as metastatic prostate cancer, it is likely that there exist many undiscovered tumor specific genetic dependencies, such as prostate cancer specific drivers, that represent drug targets. more...