GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens; Microcebus murinus

Type:

Expression profiling by array

Platform:

GPL570

59 Samples

Download data: CEL

(Submitter supplied) Parkinson disease (PD) is a neurodegenerative disease primarily associated with impaired movement affecting elderly people. To improve the understanding of the pathogenesis and to develop new therapies, we have developed a non-human primate model of PD using the lemurian Microcebus murinus (Mim). In this study, we tested the potential of canine adenovirus type 2 (CAV-2) as vector for gene transfer in the Mim brain by analyzing the gene expression changes in three regions involved in motor control: striatum, frontal cortex and midbrain. more...

Organism:

Homo sapiens; Microcebus murinus

Type:

Expression profiling by array

Platform:

GPL570

19 Samples

Download data: CEL, TXT

(Submitter supplied) Parkinson disease (PD) is a neurodegenerative disease primarily associated with impaired movement affecting elderly people. To improve the understanding of the pathogenesis and to develop new therapies, we have developed a non-human primate model of PD using the lemurian Microcebus murinus (Mim). In this study, we tested the potential of canine adenovirus type 2 (CAV-2) as vector for gene transfer in the Mim brain by analyzing the gene expression changes in three regions involved in motor control: striatum, frontal cortex and midbrain. more...

Organism:

Homo sapiens; Microcebus murinus

Type:

Expression profiling by array

Platform:

GPL570

20 Samples

Download data: CEL, TXT

(Submitter supplied) Parkinson disease (PD) is a neurodegenerative disease primarily associated with impaired movement affecting elderly people. To improve the understanding of the pathogenesis and to develop new therapies, we have developed a non-human primate model of PD using the lemurian Microcebus murinus (Mim). In this study, we tested the potential of canine adenovirus type 2 (CAV-2) as vector for gene transfer in the Mim brain by analyzing the gene expression changes in three regions involved in motor control: striatum, frontal cortex and midbrain. more...

Organism:

Homo sapiens; Microcebus murinus

Type:

Expression profiling by array

Platform:

GPL570

20 Samples

Download data: CEL, TXT

(Submitter supplied) To get insight into systemic molecular events associated with Parkinson's disease (PD), an age-related neurodegenerative disorder, we compared gene expression patterns of peripheral blood mononuclear cells (PBMC) derived from elderly healhy controls and from PD patients.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL4133

50 Samples

Download data: TXT

(Submitter supplied) With the goal of specifically dissecting the toxicogenomic signatures of the helper-dependent (HD) human (HAd5) and canine (CAV-2) adenovirus, the VSV-G-pseudotyped SIN HIV-1 (LV) and the Adenoviral-associated vector 2/9 for human neurons (AAV2/9), we transduced a bona fide human neuronal system with HD-HAd5, HD-CAV-2, LV and AAV2/9, we analysed the transcriptional response of more than 47,000 transcripts using gene chips. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4861

Platform:

GPL570

30 Samples

Download data: CEL

Temporal analysis of differentiated mNPC cultures transduced with three vectors: Helper-dependent (HD) human (HAd) and canine (CAV-2) adenoviruses and VSV-G-pseudotyped self-inactivating HIV-1 vector (LV). Results provide insight into the toxicogenomic profiles of these viral vectors in mNPCs.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 5 agent, 2 time sets

Platform:

GPL570

Series:

GSE47130

30 Samples

Download data: CEL