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scRNAseq of FACS-isolated microglia from spinal cords of Optn KO mice
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scRNAseq from spinal cords
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scRNAseq of CD45 enriched cells from spinal cords of Optn floxed and KO mice
scRNAseq from spinal cords of SOD1-G93A and WT mice
RIPK1 kinase-dependent gene expression in human astrocytes in vitro
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RIPK1 kinase-dependent gene expression in mouse microglia and astrocytes in vitro
RIPK1 kinase-dependent gene expression in mouse microglia and astrocytes in vivo during EAE
TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging
Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner
Next Generation Sequencing to check the enrichment of RIPK1/BAF on chromatin, RIPK1-dependent chromatin state and RIPK1-dependent transcriptome during inflammatory responses.
Single-cell RNA-seq analysis of the brainstem of mutant SOD1 mice reveals perturbed cell types and pathways of amyotrophic lateral sclerosis
Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of Amyotrophic Lateral Sclerosis
The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice
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Defining the microglia transcriptome during disease progression in ALS transgenic mice
Microglia-specific microarray analysis at early symptomatic age in a mouse model of amyotrophic lateral sclerosis
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Amyotrophic lateral sclerosis
NanoString miRNA profiling of peripheral blood sorted CD14+CD16- monocytes from amyotrophic lateral sclerosis, multiple sclerosis and healthy control subjects
NanoString nCounter immune-related gene expression in blood sorted CD14+CD16- monocytes from sALS, fALS and HC subjects
Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer's disease
Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model mice
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