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Links from GEO DataSets

Items: 16

1.

High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq13 (Typhi and Paratyphi A infection of THP-1 human macrophages)

(Submitter supplied) Salmonella enterica is comprised of genetically distinct “serovars”, that together provide an intriguing model for exploring the genetic basis of pathogen evolution. While the genomes of numerous Salmonella isolates with broad variations in host range and human disease manifestations have been sequenced, the functional links between genetic and phenotypic differences among these serovars remain poorly understood. more...
Organism:
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150; Salmonella enterica subsp. enterica serovar Typhi str. Ty2
Type:
Other
Platforms:
GPL34286 GPL34287
9 Samples
Download data: CSV
Series
Accession:
GSE262769
ID:
200262769
2.

High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74; Salmonella enterica subsp. enterica serovar Typhimurium str. D23580; Salmonella enterica subsp. enterica serovar Typhi str. Ty2; Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150
Type:
Other
4 related Platforms
279 Samples
Download data
Series
Accession:
GSE264519
ID:
200264519
3.

High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq9 (LB, gentamycin, cotrimoxazole, rifampicin, polymyxin B)

(Submitter supplied) Salmonella enterica is comprised of genetically distinct “serovars”, that together provide an intriguing model for exploring the genetic basis of pathogen evolution. While the genomes of numerous Salmonella isolates with broad variations in host range and human disease manifestations have been sequenced, the functional links between genetic and phenotypic differences among these serovars remain poorly understood. more...
Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74; Salmonella enterica subsp. enterica serovar Typhimurium str. D23580; Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150; Salmonella enterica subsp. enterica serovar Typhi str. Ty2
Type:
Other
4 related Platforms
48 Samples
Download data: CSV
Series
Accession:
GSE262848
ID:
200262848
4.

High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq12 (Typhimurium THP-1 infections)

(Submitter supplied) Salmonella enterica is comprised of genetically distinct “serovars”, that together provide an intriguing model for exploring the genetic basis of pathogen evolution. While the genomes of numerous Salmonella isolates with broad variations in host range and human disease manifestations have been sequenced, the functional links between genetic and phenotypic differences among these serovars remain poorly understood. more...
Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. D23580; Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74
Type:
Other
Platforms:
GPL34285 GPL34288
12 Samples
Download data: CSV
Series
Accession:
GSE262768
ID:
200262768
5.

High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq6 (anaerobic LB, GMM, zinc, Nmedia, protamine- second set)

(Submitter supplied) Salmonella enterica is comprised of genetically distinct “serovars”, that together provide an intriguing model for exploring the genetic basis of pathogen evolution. While the genomes of numerous Salmonella isolates with broad variations in host range and human disease manifestations have been sequenced, the functional links between genetic and phenotypic differences among these serovars remain poorly understood. more...
Organism:
Salmonella enterica subsp. enterica serovar Typhi str. Ty2; Salmonella enterica subsp. enterica serovar Typhimurium str. D23580; Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150; Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74
Type:
Other
4 related Platforms
28 Samples
Download data: CSV
Series
Accession:
GSE261873
ID:
200261873
6.

High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq5 (anaerobic LB, GMM, zinc, Nmedia, protamine)

(Submitter supplied) Salmonella enterica is comprised of genetically distinct “serovars”, that together provide an intriguing model for exploring the genetic basis of pathogen evolution. While the genomes of numerous Salmonella isolates with broad variations in host range and human disease manifestations have been sequenced, the functional links between genetic and phenotypic differences among these serovars remain poorly understood. more...
Organism:
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150; Salmonella enterica subsp. enterica serovar Typhi str. Ty2; Salmonella enterica subsp. enterica serovar Typhimurium str. D23580; Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74
Type:
Other
4 related Platforms
24 Samples
Download data: CSV
Series
Accession:
GSE261867
ID:
200261867
7.

High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq4 (InSPI2, hydrogen peroxide (H2O2), nitric oxide (NO), sodium hypochlorite (bleach))

(Submitter supplied) Salmonella enterica is comprised of genetically distinct “serovars”, that together provide an intriguing model for exploring the genetic basis of pathogen evolution. While the genomes of numerous Salmonella isolates with broad variations in host range and human disease manifestations have been sequenced, the functional links between genetic and phenotypic differences among these serovars remain poorly understood. more...
Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74; Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150; Salmonella enterica subsp. enterica serovar Typhimurium str. D23580; Salmonella enterica subsp. enterica serovar Typhi str. Ty2
Type:
Other
4 related Platforms
40 Samples
Download data: CSV
Series
Accession:
GSE261860
ID:
200261860
8.

High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq3 (LB, ceftriaxone, ciprofloxacin, azithromycin)

(Submitter supplied) Salmonella enterica is comprised of genetically distinct “serovars”, that together provide an intriguing model for exploring the genetic basis of pathogen evolution. While the genomes of numerous Salmonella isolates with broad variations in host range and human disease manifestations have been sequenced, the functional links between genetic and phenotypic differences among these serovars remain poorly understood. more...
Organism:
Salmonella enterica subsp. enterica serovar Typhi str. Ty2; Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150; Salmonella enterica subsp. enterica serovar Typhimurium str. D23580; Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74
Type:
Other
4 related Platforms
40 Samples
Download data: CSV
Series
Accession:
GSE261757
ID:
200261757
9.

High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq2 (Bile, iron restriction, osmotic pressure, heat)

(Submitter supplied) Salmonella enterica is comprised of genetically distinct “serovars”, that together provide an intriguing model for exploring the genetic basis of pathogen evolution. While the genomes of numerous Salmonella isolates with broad variations in host range and human disease manifestations have been sequenced, the functional links between genetic and phenotypic differences among these serovars remain poorly understood. more...
Organism:
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150; Salmonella enterica subsp. enterica serovar Typhi str. Ty2; Salmonella enterica subsp. enterica serovar Typhimurium str. D23580; Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74
Type:
Other
4 related Platforms
40 Samples
Download data: CSV
Series
Accession:
GSE261749
ID:
200261749
10.

High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq1 (NonSPI2, InSPI2, InSPI2Mg, M9glucose)

(Submitter supplied) Salmonella enterica is comprised of genetically distinct “serovars”, that together provide an intriguing model for exploring the genetic basis of pathogen evolution. While the genomes of numerous Salmonella isolates with broad variations in host range and human disease manifestations have been sequenced, the functional links between genetic and phenotypic differences among these serovars remain poorly understood. more...
Organism:
Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150; Salmonella enterica subsp. enterica serovar Typhi str. Ty2; Salmonella enterica subsp. enterica serovar Typhimurium str. D23580; Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74
Type:
Other
4 related Platforms
38 Samples
Download data: CSV
Series
Accession:
GSE261214
ID:
200261214
11.

Genome and transcriptome adaptations of S. Typhimurium

(Submitter supplied) Part of a study to determine the impact of genome evolution on host adaptation of a group of Salmonella Typhimurium. The experiment is designed to determine the impact of culture at elevated temperature on gene experssion.
Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344; Salmonella enterica subsp. enterica serovar Typhimurium
Type:
Expression profiling by array
Platform:
GPL17242
12 Samples
Download data: TXT
Series
Accession:
GSE48061
ID:
200048061
12.

Genomic comparisons of Salmonella enterica serovar Paratyphi A isolates

(Submitter supplied) Comparative genomic analysis of a temporally and locally diverse set of S. enterica ssp I sv Paratyphi A isolates Keywords: ordered
Organism:
Salmonella enterica; Salmonella enterica subsp. enterica serovar Paratyphi A
Type:
Genome variation profiling by array
Platform:
GPL1305
36 Samples
Download data
Series
Accession:
GSE1500
ID:
200001500
13.

Genomic comparison of Salmonella enterica serovars and Salmonella bongori

(Submitter supplied) This experiment set includes 64 arrays representing 26 serovars and strains of Salmonella spp. including many representatives of subspecies I, Arizona from subsp. IIIa, and S. bongori from subsp. V. The genomic DNA from all strains were labeled with Cy5 and hybridized against an equal amount (1.5 ug) of S. typhimurium SL1344 reference genomic DNA that was labeled with Cy3, all on an S. typhimurium SL1344 spotted DNA microarray. more...
Organism:
Salmonella enterica subsp. enterica serovar Typhimurium
Type:
Genome variation profiling by array
Platform:
GPL3048
64 Samples
Download data
Series
Accession:
GSE3564
ID:
200003564
14.

Gene expression profiles of primary human gall bladder epithelial cells with and without infection with S.paratyphi WT and ∆cdtB mutant for 2 and 7 days

(Submitter supplied) We have successfully established organoid culture model for human and murine gall bladder (GB) epithelial cells allowing long-time culture of primary epithelial cells. This model was used to analyze factors influencing stemness and to study infection with Salmonella paratyphi and its toxin Cdtb.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL21272 GPL4133
20 Samples
Download data: TXT
Series
Accession:
GSE100656
ID:
200100656
15.

Salmonella enterica serovar Typhimurium 4/74 transcriptomics using strand-specific RNA-seq

(Submitter supplied) Bacterial transcription networks typically consist of hundreds of transcription factors and thousands of promoters. However, current attempts to map bacterial promoters have failed to report the true complexity of bacterial transcription. The differential RNA-seq (dRNA-seq) approaches only identified a subset of promoters because they involved few growth conditions. Here, we present a simplified approach for global promoter identification in bacteria, based upon the analysis of RNA-seq data from multiple environmental conditions. more...
Organism:
Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17562
34 Samples
Download data: GR
Series
Accession:
GSE49829
ID:
200049829
16.

Genomic comparisons of Salmonella enterica sspI strains

(Submitter supplied) Comparative genomic analysis of the most important S. enterica sspI clinical isolates and respective strains from the SARB collection Keywords: other
Organism:
Salmonella enterica subsp. enterica serovar Infantis; Salmonella enterica; Salmonella enterica subsp. enterica serovar Typhisuis; Salmonella enterica subsp. enterica serovar Muenster; Salmonella enterica subsp. enterica serovar Saintpaul; Salmonella enterica subsp. enterica serovar Typhimurium; Salmonella enterica subsp. enterica serovar Dublin; Salmonella enterica subsp. enterica serovar Newport; Salmonella enterica subsp. enterica serovar Java; Salmonella enterica subsp. enterica serovar Thompson; Salmonella enterica subsp. enterica serovar Abortusovis; Salmonella enterica subsp. enterica serovar Paratyphi A; Salmonella enterica subsp. enterica serovar Paratyphi C; Salmonella enterica subsp. enterica serovar Agona; Salmonella enterica subsp. enterica serovar Typhi; Salmonella enterica subsp. enterica serovar Choleraesuis; Salmonella enterica subsp. enterica serovar Enteritidis; Salmonella enterica subsp. enterica serovar Emek; Salmonella enterica subsp. enterica serovar Gallinarum; Salmonella enterica subsp. enterica serovar Oranienburg; Salmonella enterica subsp. enterica serovar Senftenberg; Salmonella enterica subsp. enterica serovar Paratyphi B; Salmonella enterica subsp. indica; Salmonella enterica subsp. enterica serovar Montevideo; Salmonella enterica subsp. enterica serovar Muenchen; Salmonella enterica subsp. enterica serovar Heidelberg; Salmonella bongori
Type:
Genome variation profiling by array
Platforms:
GPL224 GPL548 GPL331
255 Samples
Download data
Series
Accession:
GSE1035
ID:
200001035
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