Similar studies for GEO DataSets (Select 200266880) - GEO DataSets

Select item 2002668801.

Interplay of Salmonella enterica sv. Typhimurium and Bifidobacterium infantis during co-infection of gut epithelial cells

(Submitter supplied) The deposited microarray data were generated in a study that integrated the gene expression profiles and metabolic responses of Caco2 cells incubated with Bifidobacterium infantis subsp. infantis and Salmonella enterica subsp. enterica sv. Typhimurium. The aim of this study was to investigate the interaction of B. infantis, S. Typhimurium, and host cells (Caco2) in the course of infection to understand the molecular mechanics of probiotic-pathogen-host interactions.

Organism:: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2; Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL34454 GPL570
36 Samples

Download data: CEL

Series

Accession:: GSE266880

ID:: 200266880

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000657162.

Transcriptome response of Salmonella enterica subsp. enterica serovar Typhimurium N-15 and Bifidobacterium thermophilum RBL67 in co-culture

(Submitter supplied) Bifidobacterium thermophilum RBL67 (RBL67), a human fecal isolate and promising probiotic candidate, showed antagonistic and protective effects against Salmonella and Listeria in vitro. However, the underlying mechanisms fostering these health-related effects remain unknown. Therefor the transcriptome response of RBL67 and Salmonella enterica subsp. enterica serovar Typhimurium N-15 (N-15) in co-culture compared to the response in their respective mono-cultures. more...

Organism:: Bifidobacterium thermophilum; Salmonella enterica subsp. enterica serovar Typhimurium

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL17070 GPL19749
12 Samples

Download data: XLSX

Series

Accession:: GSE65716

ID:: 200065716

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001960643.

Human Milk Oligosaccharide Utilization in Intestinal Bifidobacteria is Governed by Global Transcriptional Regulator NagR

(Submitter supplied) Bifidobacterium longum subsp. infantis (B. infantis) is a prevalent beneficial bacterium that colonizes the human neonatal gut and is uniquely adapted to efficiently use human milk oligosaccharides (HMOs) as a carbon and energy source. Multiple studies have focused on characterizing the elements of HMO utilization machinery in B. infantis; however, the regulatory mechanisms governing the expression of these catabolic pathways remain poorly understood. more...

Organism:: Bifidobacterium longum subsp. infantis

Type:: Expression profiling by high throughput sequencing

Platform:: GPL28926
12 Samples

Download data: TXT

Series

Accession:: GSE196064

ID:: 200196064

PubMed Full text in PMC Similar studies

Select item 2000640174.

RNA sequencing of CACO-2 cells incubated with Bifidobacteria breve grown on human milk oligosaccharides.

(Submitter supplied) Background: Breastfed human infants are predominantly colonized by bifidobacteria that thrive on human milk oligosaccharides (HMO). The two most predominant species of bifidobacteria in infant feces are Bifidobacterium breve (B. breve) and Bifidobacterium longum subsp. infantis (B. infantis), both avid HMO-consumer strains. Our laboratory has previously shown that B. infantis, when grown on HMO, increase adhesion to intestinal cells and increase the expression of the anti-inflammatory cytokine interleukin-10. more...