Similar studies for GEO DataSets (Select 3071) - GEO DataSets

Select item 30711.

Keloid fibroblast response to hydrocortisone in vitro

Analysis of keloid fibroblasts (FBs) treated with 1.5uM hydrocortisone (HC). Keloids are benign dermal tumors that form during protracted wound healing. HC at 1.5uM inhibits collagen and elastin synthesis in normal scar FBs but not in keloid FBs. Results provide insight into keloid pathogenesis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 2 disease state, 10 strain sets

Platform:: GPL570
Series:: GSE7890
19 Samples

Download data: CEL

DataSet

Accession:: GDS3071

ID:: 3071

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000078902.

Gene profiling of keloid fibroblasts shows altered expression in multiple fibrosis-associated pathways

(Submitter supplied) Keloids are benign tumors of the dermis that form during a protracted wound healing process. Susceptibility to keloid formation occurs predominantly in people of African and Asian descent. The key alteration(s) responsible for keloid formation has not been identified and there is no satisfactory treatment for this disorder. The altered regulatory mechanism is limited to dermal wound healing, although several diseases characterized by an exaggerated response to injury are prevalent in individuals of African ancestry. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3071
Platform:: GPL570
19 Samples

Download data: CEL

Series

Accession:: GSE7890

ID:: 200007890

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001178873.

A new understanding of the molecular pathway in human keloid fibroblasts and development of a novel treatment

(Submitter supplied) The goals of this study are to compare differential gene expression of normal and keloid fibroblasts with/without treatment using RNA sequencing (Day 1 and 5)

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21290
24 Samples

Download data: TXT

Series

Accession:: GSE117887

ID:: 200117887

Select item 2000068204.

Transcriptional signature of wounded keratinocytes reveals selective roles for ERK1/2, P38 and PI3K signalling pathways

(Submitter supplied) Covering denuded dermal surface after injury requires migration, proliferation and differentiation of skin keratinocytes. To clarify the major traits controlling these intermingled biological events, we surveyed the genomic modifications occurring during the course of a scratch closure of cultured human keratinocytes. Using a DNA microarray approach, we report the identification of 161 new markers of epidermal repair. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1521
36 Samples

Download data: TXT

Series

Accession:: GSE6820

ID:: 200006820

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