GEO DataSets

Analysis of CD133+ endothelial progenitor cells of coronary artey disease (CAD) patients after 3 months of exercise. Bone marrow derived progenitor cells with endothelial differentiation potential are fewer in CAD. Results provide insight into the impact of exercise on CD133+ cells of CAD patients.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 14 individual, 2 protocol sets

Platform:

GPL570

Series:

GSE18608

24 Samples

Download data: CEL

(Submitter supplied) Bone marrow-derived progenitor cells are under investigation for cardiovascular repair, but may be altered by disease. We identified 82 differentially expressed genes in CD133+ cells from patients with coronary artery disease (CAD) versus controls, of which 59 were found to be up-regulated and 23 down-regulated. These genes were found to be involved in carbohydrate metabolism, cellular development and signaling, molecular transport and cell differentiation. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3789

Platform:

GPL570

24 Samples

Download data: CEL

(Submitter supplied) Background: Gliomas are the most common type of primary brain tumours, and in this group glioblastomas (GBMs) are the higher-grade gliomas with fast progression and unfortunate prognosis. Two major aspects of glioma biology that contributes to its awful prognosis are the formation of new blood vessels through the process of angiogenesis and the invasion of glioma cells. Despite of advances, two-year survival for GBM patients with optimal therapy is less than 30%. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

16 Samples

Download data: CEL, CHP, TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL3904

40 Samples

Download data: GPR

(Submitter supplied) Immuno-stained (keratin 14+ basal marker) frozen prostate sections were subjected to laser-guided microdissection to isolate basal and luminal epithelial prostate cells for expression profiling. RNA was amplified using the AmpTec TRinucleotide kit (AmpTec GmBH). Expression profiling performed using the Invitrogen post-labelling kit and the CRUK whole genome array (WGA) gene set. Keywords: repeat sample

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL3904

10 Samples

Download data: GPR

(Submitter supplied) Epithelial cell cultures derived from benign and HRPC tissue biopsies were expanded in culture for 2-3 weeks. CD133+ and CD133- cells were isolated using the miltenyi magnetic bead system after adherence to collagen. CD133+ and CD133- RNA was isolated and amplified using the RiboAmp HS kit and expression profiling performed using the CRUK WGA gene set. Keywords: Tumour vs normal comparison

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL3904

28 Samples

Download data: GPR

(Submitter supplied) 6 benign TURP samples taken directly from patients were subjected to collagen digestion overnight. Epithelial cells isolated were adhered to collagen for 15 minutes. Adherent cells were passed through a magnetic bead column and cells positive for CD133 antibody were double selected. RNA was extracted from CD133+ and CD133- cells from each patient and amplified using the RiboAmp HS RNA amplification system. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL3904

12 Samples

Download data: GPR

(Submitter supplied) Gene expression profiles of human BM-MSC isolated form normal donor to elucidate potential molecular network for clinical application

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

4 Samples

Download data: CEL

(Submitter supplied) Background & Aims: In gastrointestinal stromal tumors (GIST) KIT exon 11 deletions are associated with poor prognosis. The aim of this study was to determine the gene expression profile of GIST carrying KIT exon 11 deletions and to identify genes associated with poor prognosis. Methods: Expression profiling was performed on 9 tumors with KIT exon 11 deletions and 7 without KIT exon 11 mutations using oligonucleotide microarrays. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL5345

21 Samples

Download data: TXT

(Submitter supplied) While the salutary effects of exercise training on conduit artery endothelial cells have been reported in animals and humans with cardiovascular risk factors or disease, whether a healthy endothelium is alterable with exercise training is less certain. The purpose of this study was to evaluate the impact of exercise training on transcriptional profiles in normal endothelial cells using a genome-wide microarray analysis. more...

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3533

29 Samples

Download data: CEL