GEO DataSets

Analysis of breast cancer (BC) metastases from different anatomical sites collected prior to treatment. The anatomical location of the metastatic lesion is associated with length of survival post-recurrence. Results provide insight into molecular mechanisms underlying BC site-specific metastases.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 7 tissue sets

Platform:

GPL10379

Series:

GSE46141

91 Samples

Download data: CEL

(Submitter supplied) Breast cancer molecular subtypes preferentially metastasize to specific organs and the anatomical location of the metastasis is associated with the length of survival post-recurrence. We used microarrays to provide a detailed characterization of breast cancer site-specific metastases with particular focus on identifying genes predictive of breast cancer liver metastatic proprnsity

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4761

Platform:

GPL10379

91 Samples

Download data: CEL, TXT

(Submitter supplied) We identified and validated the pivotal role for a metagene containing IFN-induced genes in association to higher metastatic potential as a function of the specific molecular subtype

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6884

123 Samples

Download data: TXT

(Submitter supplied) Intratumoral heterogeneity is a driver of breast cancer progression, but the nature of the clonal interactive network involved in this process remains unclear. Here, we optimized the use of optical barcoding to visualize and characterize 31 cancer subclones in vivo. By mapping the clonal composition of thousands of metastases in two clinically relevant sites, the lungs and liver, we found that metastases were highly polyclonal in lungs but not in the liver. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18573

30 Samples

Download data: CSV, TXT

(Submitter supplied) A secreted factor in bone marrow associated with metastatic gastric cancer was indentified through expression profiling in bone marrow of stage III and stage IV gastric adenocarcinoma.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL5639

10 Samples

Download data: GPR