Similar studies for GEO DataSets (Select 531) - GEO DataSets

Select item 5311.

Comparison of gene expression in bone marrow plasma cells of multiple myeloma patients with and without bone lesions. Osteolytic lesions increase in multiple myeloma patients.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL8300
Series:: GSE755
173 Samples

Download data

DataSet

Accession:: GDS531

ID:: 531

Select item 2000007552.

MRI lytic and no lytic lesions

(Submitter supplied) This series represents samples of multiple myeloma patients with and without bone lytic lesion by MRI. Keywords = multiple myeloma Keywords = osteolytic lesions Keywords = MRI Keywords = osteoblast Keywords = mesenchymal stem cell Keywords = Wnt signaling Keywords = DKK1 Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS531
Platform:: GPL8300
173 Samples

Download data

Series

Accession:: GSE755

ID:: 200000755

Select item 2000007543.

MRI-lytic-lesion

(Submitter supplied) This series represents samples of multiple myeloma patients with bone lytic lesion by MRI. Keywords = multiple myeloma Keywords = osteolytic lesions Keywords = MRI Keywords = osteoblast Keywords = mesenchymal stem cell Keywords = Wnt signaling Keywords = DKK1 Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL8300
137 Samples

Download data

Series

Accession:: GSE754

ID:: 200000754

Select item 2000007534.

MRI-no-lytic-lesion

(Submitter supplied) This series represents samples of multiple myeloma patients without bone lytic lesion by MRI. Keywords = multiple myeloma Keywords = osteolytic lesions Keywords = MRI Keywords = osteoblast Keywords = mesenchymal stem cell Keywords = Wnt signaling Keywords = DKK1 Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL8300
36 Samples

Download data

Series

Accession:: GSE753

ID:: 200000753

Select item 2000080665.

Dickkopf-1 is down-regulated by MYCN and inhibits neuroblastoma cell proliferation

(Submitter supplied) Neuroblastomas are tumors of the developing peripheral sympathetic nervous system, which originates from the neural crest. Twenty percent of neuroblastomas show amplification of the MYCN oncogene, which correlates with poor prognosis. The MYCN transcription factor can activate and repress gene expression. To broaden our insight in the spectrum of genes down-regulated by MYCN, we generated gene expression profiles of the neuroblastoma cell lines SHEP-21N and SKNAS-NmycER, in which MYCN activity can be regulated. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
16 Samples

Download data: CEL, CHP

Series

Accession:: GSE8066

ID:: 200008066

Select item 2000156956.

Comprehensive Homozygous Deletion Mapping of Myeloma Defines a Poor Prognosis Cell Death Gene Expression Signature

(Submitter supplied) Myeloma is a clonal malignancy of plasma cells. Poor prognosis risk is currently identified by clinical and cytogenetic features. However, these indicators do not capture all prognostic information. Gene expression analysis can be used to identify poor prognosis patients and this can be improved by combination with information about DNA level changes. Using SNP-based gene mapping in combination with global gene expression analysis we have identified homozygous deletions in genes and networks that are relevant to myeloma. more...

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome variation profiling by SNP array; SNP genotyping by SNP array

Platforms:: GPL3720 GPL3718 GPL570
583 Samples

Download data: CEL, CHP

Series

Accession:: GSE15695

ID:: 200015695

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000468167.

Gene expression data from 8 pairs of CD138+/- myeloma cell lines

(Submitter supplied) 8 pairs of myeloma cell lines were sorted by MACS CD138-microbead, and the each cell lines were divided into two fraction CD138+ and CD138-. We used microarrays to detail the global programme of gene expression in these 8 pairs of CD138+/- myeloma cell lines

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4969
Platform:: GPL6244
16 Samples

Download data: CEL, CHP

Series

Accession:: GSE46816

ID:: 200046816

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 49698.

CD138- and CD138+ MACS-sorted myeloma cell lines

Analysis of CD138+ and CD138− cells isolated from 8 multiple myeloma (MM) cell lines. The CD138- fraction is thought to represent MM stem cells. Results provide insight into the molecular bases of the CD138-/+ fractions of the MM cell lines.