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Links from GEO DataSets

Items: 3

1.
Full record GDS5811

TGFβ1 effect on gingival fibroblasts pretreated with TGFβ-associated kinase 1 inhibitor 5Z-7-Oxozeanol

Analysis of cultured gingival fibroblasts pre-treated with TGFβ-associated kinase 1 (TAK1) inhibitor (5Z)-7-Oxozeanol for 45 min prior to treatment with TGFβ1. Results provide insight into the extent to which TAK1 mediates fibroproliferative responses in gingival fibroblasts in response to TGFβ1.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 2 protocol sets
Platform:
GPL6244
Series:
GSE65069
8 Samples
Download data: CEL
2.

5Z-7-Oxozeanol inhibits the effect of TGFB1 on human gingival fibroblasts

(Submitter supplied) Microarray analysis was used to show that in gingival fibroblasts essentially all TGFB1 responsive genes were blocked by TAK inhibition
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5811
Platform:
GPL6244
8 Samples
Download data: CEL
Series
Accession:
GSE65069
ID:
200065069
3.

Whole-genome microarray analysis of human skin fibroblasts

(Submitter supplied) Connective tissue growthfactor (CTGF/CCN2) is a matricellular protein induced by transforming growth factor-beta (TGF-beta) and intimately involved with tissue repair and overexpressed in various fibrotic conditions. We have previously shown that keratinocytes in vitro downregulate TGF-beta induced expression of CTGF in fibroblasts by an interleukin-1 alfa (IL-1alfa) dependent mechanism. With this study we want to get a better overall perspective who fibroblasts respond on TGF-beta and in a TGF-Beta stinulated system, what effect addition of IL-1 alfa have. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17077
9 Samples
Download data: TXT
Series
Accession:
GSE69447
ID:
200069447
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