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Full record GDS4156

Parkinson's disease induced pluripotent stem cell model with triplication of the α-synuclein locus

Analysis of iPSC lines derived from a PD patient with SNCA triplication and an unaffected first-degree relative. Triplication of SNCA, encoding α-synuclein, causes an aggressive form of PD. Results provide insight into the mechanistic basis of neurodegeneration caused by α-synuclein dysfunction.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 cell line, 2 cell type, 3 genotype/variation sets
Platform:
GPL570
Series:
GSE30792
5 Samples
Download data: CEL

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