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Full record GDS4401

H9 hESC-derived neural stem cells harboring pathogenic leucine-rich repeat kinase 2 mutation

Analysis of LRRK2 (Gly2019Ser) mutant neural stem cells (NSC) treated with LRRK2 kinase specific inhibitor LRRK2-IN-1. The LRRK2 (G2019S) mutation causes familial Parkinson's disease. Results provide insight into molecular basis of progressive degeneration of NSCs caused by pathogenic LRRK2.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 2 genotype/variation sets
Platform:
GPL571
Series:
GSE36321
9 Samples
Download data: CEL

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