Bacterial cell wall component MDP effect on HEK293 cells expressing Crohn's disease-associated NOD2 variant L1007fsinsC receptor: time course - - GEO DataSets

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Bacterial cell wall component MDP effect on HEK293 cells expressing Crohn's disease-associated NOD2 variant L1007fsinsC receptor: time course

Temporal analysis of HEK293 cells stably-expressing wildtype NOD2 receptor or variant NOD2L1007fsinsC and treated with muramyl dipeptide (MDP). MDP-induced NOD2 activation induces inflammatory and antibacterial factors. Results provide insight into molecular basis of NOD2-mediated immune response.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 3 genotype/variation, 3 time sets

Platform:: GPL570
Series:: GSE22611
27 Samples

Download data: CEL

DataSet

Accession:: GDS4416

ID:: 4416

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